Evidence map›Paper›PMID 35404116›Full record

ArticlemBio2022

PMRT1, a

Jan Stephan Wichers, Paolo Mesén-Ramírez, Gwendolin Fuchs, Jing Yu-Strzelczyk, Jan Stäcker, Heidrun von Thien, Arne Alder, Isabelle Henshall, Benjamin Liffner, Georg Nagel and 7 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Identification of a divalent metal transporter required for cellular iron metabolism in malaria parasites.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Iron transport pathways in the human malaria parasiteFrontiers in cellular and infection microbiology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Updated List of Transport Proteins inFrontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 2 countries.

Jan Stephan WichersCentre for Structural Systems Biology, Hamburg, Germany.ORCID 0000-0002-0599-1742
Paolo Mesén-RamírezBernhard Nocht Institute for Tropical Medicinegrid.424065.1, Hamburg, Germany.ORCID 0000-0001-7842-5867
Gwendolin FuchsCentre for Structural Systems Biology, Hamburg, Germany.ORCID 0000-0001-9294-6984
Jing Yu-StrzelczykInstitute of Physiology, Department of Neurophysiology, Biocenter, University of Würzburg, Würzburg, Germany.ORCID 0000-0002-7576-6831
Jan StäckerBernhard Nocht Institute for Tropical Medicinegrid.424065.1, Hamburg, Germany.ORCID 0000-0002-4738-6639
Heidrun von ThienCentre for Structural Systems Biology, Hamburg, Germany.
Arne AlderCentre for Structural Systems Biology, Hamburg, Germany.ORCID 0000-0003-4918-4640
Isabelle HenshallResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaidegrid.1010.0, Adelaide, Australia.ORCID 0000-0002-5906-0687
Benjamin LiffnerResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaidegrid.1010.0, Adelaide, Australia.ORCID 0000-0002-1573-6139
Georg NagelInstitute of Physiology, Department of Neurophysiology, Biocenter, University of Würzburg, Würzburg, Germany.ORCID 0000-0001-8174-8712
Christian LöwCentre for Structural Systems Biology, Hamburg, Germany.ORCID 0000-0003-0764-7483
Danny WilsonResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaidegrid.1010.0, Adelaide, Australia.
Tobias SpielmannBernhard Nocht Institute for Tropical Medicinegrid.424065.1, Hamburg, Germany.ORCID 0000-0002-3968-4601
Shiqiang GaoInstitute of Physiology, Department of Neurophysiology, Biocenter, University of Würzburg, Würzburg, Germany.ORCID 0000-0001-6190-9443
Tim-Wolf GilbergerCentre for Structural Systems Biology, Hamburg, Germany.
Anna Bachmann *Centre for Structural Systems Biology, Hamburg, Germany.ORCID 0000-0001-8397-7308
Jan Strauss *Centre for Structural Systems Biology, Hamburg, Germany.ORCID 0000-0002-6208-791X
Universität Hamburg · DEBernhard Nocht Institute for Tropical Medicine · DEUniversity of Würzburg · DEThe University of Adelaide · AUBurnet Institute · AUCentre for Structural Systems Biology · DEEuropean Molecular Biology Laboratory · DE

Funding

Australian Government (Federal Government)Centre for Structural Systems Biology (CSSB) KIF 2019/002Deutsche Forschungsgemeinschaft (DFG) 374031971 TRR 240 A04Deutsche Forschungsgemeinschaft (DFG) BA 5213/3-1Deutsche Forschungsgemeinschaft (DFG) SP1209/4-1Deutscher Akademischer Austauschdienst (DAAD)Hospital Research Foundation (THRF)Jürgen Manchot Stiftung (Jürgen Manchot Foundation)Partnership of University of Hamburg and DESY (PIER) PIF-2018-87
6 · The paper itself

Abstract

Membrane transport proteins perform crucial roles in cell physiology. The obligate intracellular parasite Plasmodium falciparum, an agent of human malaria, relies on membrane transport proteins for the uptake of nutrients from the host, disposal of metabolic waste, exchange of metabolites between organelles, and generation and maintenance of transmembrane electrochemical gradients for its growth and replication within human erythrocytes. Despite their importance for

Indexed as

Malaria, FalciparumParasitesPlasmodiumAnimalsCell MembraneHumansMembrane Transport ProteinsPlasmodium falciparumMembrane Transport Proteinsapicomplexan parasitesmembrane proteinsmembrane transportPlasmodium falciparumreverse genetic analysissubcellular localizationtransporters

Identifiers

PMID35404116
PMCPMC9040750
OpenAlexW4226000753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.