ArticlePlant biotechnology journal2022
The OsEIL1-OsERF115-target gene regulatory module controls grain size and weight in rice.
Article in Plant biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 69 citations in OpenAlex.
- The OsRhoGAP2-OsRAC5 complex regulates rice seed germination via modulating aleurone layer development and α-amylase activity.Plant cell reports · 2026Article
- Fine mapping and candidate gene analysis of a major QTL qHSW_11 for seed weight in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Regulatory factors of starch metabolism in cereal endosperm.Plant molecular biology · 2026Review
- FAD-Linked Oxidoreductase Protein 1 (FLO1) Coordinates Grain Development and Drought Tolerance in Rice.Plants (Basel, Switzerland) · 2026Article
- A soybean EIN transcription factor confers resistance to Phytophthora sojae and favorable agronomic traits.Plant cell reports · 2026Article
- OsSAE1 orchestrates the antagonistical regulation of gibberellin and abscisic acid signaling to control rice seed germination.Journal of integrative plant biology · 2026Article
- Dual-Layer Transcriptional-Protein Regulation by HvAP2-12 Represses HvAP2-18 Activity to Fine-Tune Barley Starch Synthesis.Plant biotechnology journal · 2025Article
- Research Advances in AP2/ERF Transcription Factors in Rice Growth and Development.Plants (Basel, Switzerland) · 2025Review
- Genome-Wide Identification of the RhoGAP Gene Family and Main Function of OsRhoGAP2 in Seed Germination of Rice by Transcriptome Analysis.Rice (New York, N.Y.) · 2025Article
- Identification of an adaptor protein 2σ gene for OsTGW12 to determine grain weight and potentiate quality breeding in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Recent advances in improving yield and immunity through transcription factor engineering.Journal of integrative plant biology · 2025Review
- Evolution of ANT family and regulation of lint percentage by the GhAIL6-GhTPL1 module.Frontiers in plant science · 2025Article
- NAC25 transcription factor regulates the degeneration of cytoplasmic membrane integrity and starch biosynthesis in rice endosperm through interacting with MADS29.Frontiers in plant science · 2025Article
- Paralogous Gene Recruitment in Multiple Families Constitutes Genetic Architecture and Robustness of Pod Dehiscence in Legumes.Genome biology and evolution · 2024Article
- Ethylene in fruits: beyond ripening control.Horticulture research · 2024Article
- Characterization and Transcriptomic Analysis of Sorghum EIN/EIL Family and Identification of Their Roles in Internode Maturation.Plants (Basel, Switzerland) · 2024Article
- Molecular mechanisms controlling grain size and weight and their biotechnological breeding applications in maize and other cereal crops.Journal of advanced research · 2024Review
- Overexpression of OsACL5 triggers environmentally-dependent leaf rolling and reduces grain size in rice.Plant biotechnology journal · 2024Article
- DGW1, encoding an hnRNP-like RNA binding protein, positively regulates grain size and weight by interacting with GW6 mRNA.Plant biotechnology journal · 2024Article
- Integration of mRNA and miRNA analysis reveals the molecular mechanisms of sugar beet (Beta vulgaris L.) response to salt stress.Scientific reports · 2023Article
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Authors and funding
24 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Grain size is one of the essential determinants of rice yield. Our previous studies revealed that ethylene plays an important role in grain-size control; however, the precise mechanism remains to be determined. Here, we report that the ethylene response factor OsERF115 functions as a key downstream regulator for ethylene-mediated grain development. OsERF115 encodes an AP2/ERF-type transcriptional factor that is specifically expressed in young spikelets and developing caryopses. Overexpression of OsERF115 significantly increases grain length, width, thickness and weight by promoting longitudinal elongation and transverse division of spikelet hull cells, as well as enhancing grain-filling activity, whereas its knockout mutations lead to the opposite effects, suggesting that OsERF115 positively regulates grain size and weight. OsERF115 transcription is strongly induced by ethylene, and OsEIL1 directly binds to the promoter to activate its expression. OsERF115 acts as a transcriptional repressor to directly or indirectly modulate a set of grain-size genes during spikelet growth and endosperm development. Importantly, haplotype analysis reveals that the SNP variations in the EIN3-binding sites of OsERF115 promoter are significantly associated with the OsERF115 expression levels and grain weight, suggesting that natural variations in the OsERF115 promoter contribute to grain-size diversity. In addition, the OsERF115 orthologues are identified only in grass species, implying a conserved and unique role in the grain development of cereal crops. Our results provide insights into the molecular mechanism of ethylene-mediated grain-size control and a potential strategy based on the OsEIL1-OsERF115-target gene regulatory module for genetic improvement of rice yield.
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