Evidence map›Paper›PMID 35403792›Full record

ArticleDiabetes, obesity & metabolism2022

Comparison of MiniMed 780G system performance in users aged younger and older than 15 years: Evidence from 12 870 real-world users.

Arcelia Arrieta, Tadej Battelino, Andrea E Scaramuzza, Julien Da Silva, Javier Castañeda, Toni L Cordero, John Shin, Ohad Cohen

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 69 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 5 pooled it
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06130215 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Evaluation on Glycemic Control Using Two Different Meal Announcement Plans in Adolescents With Type 1 Diabetes on Minimed 780G Hybrid Closed Loop System

TypeinterventionalSponsorSidra MedicineRan2023 to 2025Enrolled34ConditionsType 1 DiabetesArmsSimple meal management, Precise meal management
NCT06600776 phase4not yet recruitingnot on this mapstarted 2024, after this paper: background citation

A Pilot Study Comparing the Efficacy of Dosing Ultra Rapid Insulin Lispro in a Medtronic 780G Hybrid Closed Loop System at Mealtime or Postmeal

TypeinterventionalSponsorTel-Aviv Sourasky Medical CenterRan2024 to 2025Enrolled50ConditionsType 1 Diabetes (T1D)ArmsUltra Rapid Lispro (URLi), Insulin pump with continuous glucose monitoring (CGM)
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 5 syntheses or guidelines pooled it, 147 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Real-World Evidence of Automated Insulin Delivery System Use.Diabetes technology & therapeutics · 2024
    Pooled it
  4. Guideline
  5. Pooled it
  6. Trial
  7. Trial
  8. Real-World Glucometric Outcomes of the MiniMed 780G Advanced Hybrid Closed-Loop System in Users with Type 1 Diabetes in Spain.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Article
  9. Real-World Performance of the MiniMed 780G Advanced Hybrid Closed Loop Automated Insulin Delivery System in Greece.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Observational

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 6 countries.

Arcelia ArrietaMedtronic Bakken Research Center, Maastricht, The Netherlands.
Tadej BattelinoUniversity Children's Hospital, University Medical Centre Ljubljana and Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.ORCID 0000-0002-0273-4732
Andrea E ScaramuzzaDiabetes, Endocrinology and Nutrition Service, Division of Pediatrics, ASST Cremona, Maggiore Hospital, Cremona, Italy.ORCID 0000-0002-1518-8515
Julien Da SilvaMedtronic International Trading Sàrl, Tolochenaz, Switzerland.
Javier CastañedaMedtronic Bakken Research Center, Maastricht, The Netherlands.
Toni L CorderoMedtronic, Northridge, California.ORCID 0000-0003-4597-4194
John ShinMedtronic, Northridge, California.
Ohad CohenMedtronic International Trading Sàrl, Tolochenaz, Switzerland.ORCID 0000-0003-4337-1795
Medtronic (Ireland) · IEMedtronic (Netherlands) · NLMedtronic (Switzerland) · CHIstituti Ospitalieri di Cremona · ITUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate real-world glycaemic outcomes and goals achieved by users of the MiniMed 780G advanced hybrid closed loop (AHCL) system aged younger and older than 15 years with type 1 diabetes (T1D). MATERIALS AND

methodsData uploaded by MiniMed 780G system users from 27 August 2020 to 22 July 2021 were aggregated and retrospectively analysed based on self-reported age (≤15 years and >15 years) for three cohorts: (a) post-AHCL initiation, (b) 6-month longitudinal post-AHCL initiation and (c) pre- versus post-AHCL initiation. Analyses included mean percentage of time spent in AHCL and at sensor glucose ranges, insulin delivered and the proportion of users achieving recommended glucose management indicator (GMI < 7.0%) and time in target range (TIR 70-180 mg/dl > 70%) goals.

resultsUsers aged 15 years or younger (N = 3211) achieved a GMI of 6.8% ± 0.3% and TIR of 73.9% ± 8.7%, while spending 92.7% of time in AHCL. Users aged older than 15 years (N = 8874) achieved a GMI of 6.8% ± 0.4% and TIR of 76.5% ± 9.4% with 92.3% of time in AHCL. Time spent at less than 70 mg/dl was within the recommended target of less than 4% (3.2% and 2.3%, respectively). Similar outcomes were observed for each group (N = 790 and N = 1642, respectively) in the first month following AHCL initiation, and were sustained over the 6-month observation period.

conclusionsThis real-world analysis shows that more than 75% of users with T1D aged 15 years or younger using the MiniMed 780G system achieved international consensus-recommended glycaemic control, mirroring the achievements of the population aged older than 15 years.

Indexed as

Diabetes Mellitus, Type 1Insulin Infusion SystemsBlood GlucoseBlood Glucose Self-MonitoringGlucoseHumansHypoglycemic AgentsInsulinRetrospective StudiesBlood GlucoseGlucoseHypoglycemic AgentsInsulinadolescentsautomated insulin deliveryclosed-loop systemdiabetesglucose management indicatorhyperglycaemiahypoglycaemiapaediatricreal-world evidencetime in range

Identifiers

PMID35403792
PMCPMC9545031
OpenAlexW4223439323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.