ArticleThe Journal of infectious diseases2022
Comparable Pregnancy Outcomes for HIV-Uninfected and HIV-Infected Women on Antiretroviral Treatment in Kenya.
Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- Prenatal exposure to HIV pre-exposure prophylaxis and birth, growth, and social-emotional developmental outcomes throughout early childhood in Kenya: a prospective cohort study.The Lancet. Global health · 2025Trial
- Maternal liver function and adverse pregnancy outcomes in Chinese women with HIV: a cohort study.BMC public health · 2026Article
- Impact of maternal HIV infection on pregnancy and labor complication and perinatal health outcomes: a South African retrospective study.Archives of gynecology and obstetrics · 2026Article
- Abortion and its association with antiretroviral therapy among young women living with HIV in northern Uganda: a cross-sectional study.AIDS research and therapy · 2025Article
- Obstetric and newborn outcomes of mothers with and without HIV infection in Anaka general hospital in Northern Uganda.PloS one · 2025Article
- Hepatitis C Prevalence and Birth Outcomes among Pregnant Women in the United States: A 2010-2020 Population Study.Pathogens (Basel, Switzerland) · 2024Article
- Prevalence and factors associated with anaemia among pregnant women attending antenatal care in a district hospital and its feeder community healthcare centre of the Limpopo Province, South Africa.Journal of family medicine and primary care · 2023Article
- Factors associated with adverse pregnancy outcomes of maternal syphilis in Henan, China, 2016-2022.Epidemiology and infection · 2023Article
- Article
- Dolutegravir and pregnancy outcomes including neural tube defects in the USA during 2008-20: a national cohort study.The lancet. HIV · 2023Article
- Thirty years of HIV pregnancies in French Guiana: prevention successes and remaining obstetrical challenges.Frontiers in global women's health · 2023Article
- Adverse pregnancy outcomes associated with antiretroviral therapy initiated before pregnancy and during pregnancy: a retrospective study in Hubei province, China.Frontiers in medicine · 2023Article
- Microcephaly and Associated Risk Factors in Newborns: A Systematic Review and Meta-Analysis Study.Tropical medicine and infectious disease · 2022Review
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Authors and funding
20 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundThe impact of human immunodeficiency virus (HIV) on pregnancy outcomes for women on antiretroviral therapy (ART) in sub-Saharan Africa remains unclear.
methodsPregnant women in Kenya were enrolled in the second trimester and followed up to delivery. We estimated effects of treated HIV with 3 pregnancy outcomes: loss, premature birth, and low birth weight and factors associated with HIV-positive status.
resultsOf 2113 participants, 311 (15%) were HIV infected and on ART. Ninety-one of 1762 (5%) experienced a pregnancy loss, 169/1725 (10%) a premature birth (<37 weeks), and 74/1317 (6%) had a low-birth-weight newborn (<2500 g). There was no evidence of associations between treated HIV infection and pregnancy loss (adjusted relative risk [aRR], 1.19; 95% confidence interval [CI], .65-2.16; P = .57), prematurity (aRR, 1.09; 95% CI, .70-1.70; P = .69), and low birth weight (aRR, 1.36; 95% CI, .77-2.40; P = .27). Factors associated with an HIV-positive status included older age, food insecurity, lower education level, higher parity, lower gestation at first antenatal clinic, anemia, and syphilis. Women who were overweight or underweight were less likely to be HIV infected compared to those with normal weight.
conclusionsCurrently treated HIV was not significantly associated with adverse pregnancy outcomes. HIV-infected women, however, had a higher prevalence of other factors associated with adverse pregnancy outcomes.
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