Evidence map›Paper›PMID 35403443›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Predictive Values of the Selected Inflammatory Indexes in Colon Cancer.

Li Huang, Zuojian Hu, Ruixian Luo, Hailan Li, Ziji Yang, Xue Qin, Zhuning Mo

Abstract read
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Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Li HuangDepartment of Clinical Laboratory, 117742First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zuojian HuDepartment of Clinical Laboratory, 117742First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Ruixian LuoDepartment of Blood Transfusion, 477292Guangxi Academy of Medical Sciences and the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Hailan LiDepartment of Blood Transfusion, 477292Guangxi Academy of Medical Sciences and the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Ziji YangDepartment of Blood Transfusion, 477292Guangxi Academy of Medical Sciences and the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Xue QinDepartment of Clinical Laboratory, 117742First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zhuning MoDepartment of Blood Transfusion, 477292Guangxi Academy of Medical Sciences and the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.ORCID https://orcid.org/0000-0001-9627-5241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAmple evidence has revealed that the lymphocyte-to-monocyte ratio (LMR), albumin-to-globulin ratio (AGR), and mean platelet volume (MPV) are cancer-related inflammatory markers. The present study aimed to combine these indicators to better assess the progression of colon cancer.

methodsThis retrospective study enrolled 251 patients with colon cancer, 171 patients with benign colon diseases, and 187 healthy control subjects. The receiver operating characteristic curve and area under the curve (AUC) were used to determine the diagnostic values of the selected inflammatory index.

resultsThe levels of LMR, AGR, and MPV were decreased in the colon cancer group compared with the healthy control and benign colon disease groups. The LMR, AGR, and MPV were all correlated with tumor size. Moreover, LMR and AGR was associated with lymph node metastasis and clinical stage, AGR was related to distant metastasis. Both the LMR (

conclusionsCEA combined with the LMR, AGR, or MPV may be used as better blood-based biomarkers in the progression of colon cancer patients.

Indexed as

Carcinoembryonic AntigenColonic NeoplasmsHumansLymphocytesMonocytesRetrospective StudiesCarcinoembryonic Antigenalbumin-to-globulin ratiocolon cancerdiagnosislymphocyte-to-monocyte ratiomean platelet volume

Identifiers

PMID35403443
PMCPMC9006378

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.