Evidence map›Paper›PMID 35403130›Full record

ArticleCancer diagnosis & prognosis

Cannabidiol Μay Prolong Survival in Patients With Glioblastoma Multiforme.

Rudolf Likar, Markus Koestenberger, Martin Stutschnig, Gerhard Nahler

Open access · greenAbstract read
In one paragraph

Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Cannabinoids in the treatment of glioblastoma.Pharmacological reports : PR · 2024
    Review
  5. Review
  6. The therapeutic potential of purified cannabidiol.Journal of cannabis research · 2023
    Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Rudolf LikarAbteilung für Anästhesiologie und Intensivmedizin, Klinikum Klagenfurt am Wörthersee,Klagenfurt am Wörthersee, Austria.
Markus KoestenbergerAbteilung für Anästhesiologie und Intensivmedizin, Klinikum Klagenfurt am Wörthersee,Klagenfurt am Wörthersee, Austria.
Martin StutschnigNeurologische Abteilung, Klinikum Klagenfurt am Wörthersee, Klagenfurt am Wörthersee, Austria.
Gerhard NahlerCIS Clinical Investigation Support GmbH, Vienna, Austria.
Clinical Investigation Support (Austria) · ATKlinikum Klagenfurt · ATMedical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Glioblastoma multiforme (GBM) is a relatively rare type of brain tumour with an incidence rate around 6 per 100,000. Even with the widely practiced combination of radiotherapy with adjuvant temozolomide, the median overall survival remains low with just 13.5 to 16 months after diagnosis. Patients and Methods: We retrospectively reviewed the survival of a cohort of 15 consecutive, unselected patients with histopathologically confirmed glioblastoma multiforme (GBM) who received CBD (400 to 600 mg orally per day) in addition to standard therapy (maximum resection of the tumour followed by radio-chemotherapy). Results: Of 15 patients, seven (46.7%) are now living for at least 24 months, and four (26.7%) for at least 36 months. This is more than twice as long as has been previously reported in the literature. The mean overall survival is currently 24.2 months (median 21 months). Conclusion: CBD is a well supported co-medication and seems to prolong the survival of patients with glioblastoma multiforme.

Indexed as

brain tumourCannabidiolCBDglioblastoma multiformeoverall survival

Identifiers

PMID35403130
PMCPMC8962767
OpenAlexW3210622958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.