Evidence map›Paper›PMID 35403097›Full record

ArticleFrontiers in genome editing2022

Imaging Unique DNA Sequences in Individual Cells Using a CRISPR-Cas9-Based, Split Luciferase Biosensor.

Nicholas G Heath, Henriette O'Geen, Nicole B Halmai, Jacob E Corn, David J Segal

Abstract read
In one paragraph

Article in Frontiers in genome editing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. CRISPR-Based Split Luciferase as a Biosensor for Unique DNA Sequences In Situ.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas G HeathGenome Center and Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, United States.
Henriette O'GeenGenome Center and Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, United States.
Nicole B HalmaiGenome Center and Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, United States.
Jacob E CornInnovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States.
David J SegalGenome Center and Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An extensive arsenal of biosensing tools has been developed based on the clustered regularly interspaced short palindromic repeat (CRISPR) platform, including those that detect specific DNA sequences both

Indexed as

CRISPRdCas9live cell imagingsingle gene locussplit reporter

Identifiers

PMID35403097
PMCPMC8990833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.