Evidence map›Paper›PMID 35403067›Full record

ArticleBrain, behavior, & immunity - health2022

Psychosocial and behavioral factors affecting inflammation among pregnant African American women.

Nadia Saadat, Liying Zhang, Suzanne Hyer, Vasantha Padmanabhan, Jennifer Woo, Christopher G Engeland, Dawn P Misra, Carmen Giurgescu

Open access · goldAbstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Biomarkers of reproductive psychiatric disorders.The British journal of psychiatry : the journal of mental science · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Nadia SaadatUniversity of Michigan, USA.
Liying ZhangWayne State University, USA.
Suzanne HyerUniversity of Central Florida, USA.
Vasantha PadmanabhanUniversity of Michigan, USA.
Jennifer WooTexas Woman's University, USA.
Christopher G EngelandPennsylvania State University, USA.
Dawn P MisraMichigan State University, USA.
Carmen GiurgescuUniversity of Central Florida, USA.
University of Central Florida · USUniversity of Michigan · USMichigan State University · USPennsylvania State University · USTexas Woman's University · USWayne State University · US

Funding

Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Postdoc Stipend Supplement: Developmental Origins of Metabolic Disorders T32T32DK071212 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON, Kanakadurga Singer · 2005 to 2026
$5.4M
Social Stressors and Inflammation: A Mixed Methods Approach to Preterm BirthR01MD011575 · NIMHD · UNIVERSITY OF CENTRAL FLORIDA · PI GIURGESCU, CARMEN · 2017 to 2021
$3.9M
NIDDK NIH HHS T32 DK071212NIEHS NIH HHS P30 ES017885NIMHD NIH HHS R01 MD011575
6 · The paper itself

Abstract

African American women are reported to have greater inflammation compared with women from other racial groups. Higher inflammation during pregnancy has been associated with increased risk of adverse perinatal outcomes. We hypothesized that maternal inflammation is related to depressive symptoms and social and behavioral risk factors among pregnant African American women. Pregnant African American women (n ​= ​187) were recruited at prenatal clinics in the Midwest. Women completed questionnaires and had blood drawn at a prenatal visit. Plasma levels of cytokines (interferon gamma [IFN]-γ, interleukin [IL]-6, IL-8, IL-10, tumor necrosis factor [TNF]-α) and C-reactive protein (CRP) were measured by multiplex assays. Women had a mean age of 26.58±5.42 years and a mean gestational age at data collection of 16.35±5.95 weeks. Twenty-six percent of women had Center for Epidemiological Studies-Depression (CES-D) scores ≥23 (scores that have been correlated with clinical diagnosis of depression), 15.5% smoked cigarettes, 16.6% used marijuana, and 5.3% reported experiencing intimate partner violence (IPV). Higher CES-D scores were correlated with higher plasma CRP levels (

Indexed as

African AmericanCigarette smokingCRPCytokineDepressive symptomsIntimate partner violencePregnancySubstance use

Identifiers

PMID35403067
PMCPMC8990056
OpenAlexW4221047852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.