ArticleAdvances in pharmacological and pharmaceutical sciences2022
Cytotoxicity against Human Hepatocellular Carcinoma (HepG2) Cells and Anti-Oxidant Activity of Selected Endemic or Medicinal Plants in Sri Lanka.
Article in Advances in pharmacological and pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Synthesis, in-vitro and in-silico bioactivity and computational studies of pyrene and p-methoxycinnamaldehyde linked 4-hydroxycoumarins.Scientific reports · 2026Article
- The HepG2 Cell Line as a Model for Studying Metabolic Dysfunction-Associated Steatotic Liver Disease.International journal of molecular sciences · 2026Review
- Fig Leaf Bioactivity and Safety: Temperature Optimization and FTIR Authentication.Food science & nutrition · 2026Article
- Integrated GC-MS Profiling and Phytosynthesis of MnOChemistry & biodiversity · 2026Article
- Phytochemical Profiling and Anticancer Potential ofAnti-cancer agents in medicinal chemistry · 2026Article
- A Review on Nanotechnologically Derived Phytomedicines for the Treatment of Hepatocellular Carcinoma: Recent Advances in Molecular Mechanism and Drug Targeting.Current drug targets · 2025Review
- Anti-Inflammatory, Cytotoxic, and Genotoxic Effects of Soybean Oligopeptides Conjugated with Mannose.Foods (Basel, Switzerland) · 2024Article
- Article
- Isolation, Characterization of Pyraclostrobin Derived from Soil ActinomyceteAntibiotics (Basel, Switzerland) · 2023Article
- Phytochemical profiling and cytotoxic potential of Arnebia nobilis root extracts against hepatocellular carcinoma using in-vitro and in-silico approaches.Scientific reports · 2023Article
- Chemosensing Properties of Coumarin Derivatives: Promising Agents with Diverse Pharmacological Properties, Docking and DFT Investigation.Molecules (Basel, Switzerland) · 2022Article
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Authors and funding
7 authors.
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Abstract
Hepatocellular carcinoma (HCC) is the most fatal cancer globally with limited treatment options. Plants and herbs have been used to treat cancer and other diseases for a long time by traditional practitioners in Sri Lanka. In the present study, leaf and bark extracts of selected plants were investigated for cytotoxic properties on HepG2 cells. Anti-oxidant activity and total phenolic and flavonoid contents were also determined. Plant extracts that exerted cytotoxic effects on the HepG2 cell line with IC
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