ArticleiScience2022
Open access · goldAbstract read
In one paragraph
Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 55 citations in OpenAlex.
- Transposable element regulation in mammalian germ cells and other contexts: multilayered repression, fertility, and regulated activation.Epigenomics · 2026Review
- A new integrated genetic and transcriptomic approach for investigating DUX4 and DUX4C.Journal of human genetics · 2026Article
- The multi-omics regulatory landscape of human early embryogenesis.Cellular and molecular life sciences : CMLS · 2026Review
- OTX2 inhibits human pluripotent stem cell reprogramming toward 8-cell-like and morula-like states.Nature communications · 2026Article
- Genome-wide analysis of FSHD cell lines using Nanopore sequencing reveals allele-specific differences at DUX4 target genes and complex repeats.bioRxiv : the preprint server for biology · 2025Article
- Review
- Maternal factor OTX2 regulates human embryonic genome activation and early development.Nature genetics · 2025Article
- Epigenome dynamics in early mammalian embryogenesis.Nature reviews. Genetics · 2025Review
- DUX4 at 25: how it emerged from "junk DNA" to become the cause of facioscapulohumeral muscular dystrophy.Skeletal muscle · 2025Review
- Emerging Functions of the Repeat Genome in Nuclear Structure: A View from the Human Karyotype.Annual review of genomics and human genetics · 2025Review
- Proteogenomic reprogramming to a functional human blastomere-like stem cell state via a PARP-DUX4 regulatory axis.Cell reports · 2025Article
- DUX4 activates common and context-specific intergenic transcripts and isoforms.Science advances · 2025Article
- The Unexplored Role of Connexin Hemichannels in Promoting Facioscapulohumeral Muscular Dystrophy Progression.International journal of molecular sciences · 2025Review
- Rise and SINE: roles of transcription factors and retrotransposons in zygotic genome activation.Nature reviews. Molecular cell biology · 2025Article
- Temporal variation in p38-mediated regulation of DUX4 in facioscapulohumeral muscular dystrophy.Scientific reports · 2024Article
- Kick-starting the zygotic genome: licensors, specifiers, and beyond.EMBO reports · 2024Review
- D4Z4 Hypomethylation in Human Germ Cells.Cells · 2024Article
- Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere damage repair.Journal of molecular cell biology · 2024Article
- Review
- Interaction network of human early embryonic transcription factors.EMBO reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors at 9 institutions in 7 countries.
Sanna VuoristoDepartment of Biosciences and Nutrition, Karolinska Institutet, 17177 Huddinge, Sweden.
Shruti BhagatDepartment of Biosciences and Nutrition, Karolinska Institutet, 17177 Huddinge, Sweden.
Christel Hydén-GranskogReproductive Medicine Unit, Helsinki University Hospital, 00290 Helsinki, Finland.
Masahito YoshiharaDepartment of Biosciences and Nutrition, Karolinska Institutet, 17177 Huddinge, Sweden.
Lisa GawriyskiInstitute of Biotechnology, University of Helsinki, 00790 Helsinki, Finland.
Eeva-Mari JouhilahtiStem Cells and Metabolism Research Program, University of Helsinki, 00014 Helsinki, Finland.
Vipin RangaStructural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, 20520 Turku, Finland.
Mahlet TamiratStructural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, 20520 Turku, Finland.
Mikko HuhtalaStructural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, 20520 Turku, Finland.
Ida KirjanovDepartment of Obstetrics and Gynecology, 00014, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland.
Sonja NykänenDepartment of Obstetrics and Gynecology, 00014, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland.
Kaarel KrjutškovDepartment of Biosciences and Nutrition, Karolinska Institutet, 17177 Huddinge, Sweden.
Anastassius DamdimopoulosKarolinska Institutet, Bioinformatics and Expression Analysis Core Facility, 17177 Huddinge, Sweden.
Jere WeltnerStem Cells and Metabolism Research Program, University of Helsinki, 00014 Helsinki, Finland.
Kosuke HashimotoRIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.
Gaëlle RecherLaboratoire Photonique Numérique et Nanosciences, CNRS, Institut d'Optique Graduate School, University of Bordeaux, UMR 5298, 33400 Bordeaux, France.
Sini EzerStem Cells and Metabolism Research Program, University of Helsinki, 00014 Helsinki, Finland.
Priit PaluojaCompetence Centre for Health Technologies, 51010 Tartu, Estonia.
Pauliina PaloviitaDepartment of Obstetrics and Gynecology, 00014, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland.
Yujiro TakegamiK.K. DNAFORM, Yokohama 230-0051, Japan.
Ai KanemaruK.K. DNAFORM, Yokohama 230-0051, Japan.
Karolina LundinDepartment of Obstetrics and Gynecology, 00014, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland.
Tomi T AirenneStructural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, 20520 Turku, Finland.
Timo OtonkoskiStem Cells and Metabolism Research Program, University of Helsinki, 00014 Helsinki, Finland.
Juha S TapanainenDepartment of Obstetrics and Gynecology, 00014, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland.
Hideya KawajiRIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.
Yasuhiro MurakawaRIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.
Thomas R BürglinDepartment of Biomedicine, University of Basel, 4031 Basel, Switzerland.
Markku VarjosaloInstitute of Biotechnology, University of Helsinki, 00790 Helsinki, Finland.
Mark S JohnsonStructural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, 20520 Turku, Finland.
Timo TuuriDepartment of Obstetrics and Gynecology, 00014, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland.
Shintaro KatayamaDepartment of Biosciences and Nutrition, Karolinska Institutet, 17177 Huddinge, Sweden.
Juha KereDepartment of Biosciences and Nutrition, Karolinska Institutet, 17177 Huddinge, Sweden.
University of Helsinki · FIÅbo Akademi University · FIKarolinska Institutet · SEKyoto University · JPCentre National de la Recherche Scientifique · FRHelsinki University Hospital · FIRIKEN Center for Integrative Medical Sciences · JPTokyo Metropolitan Institute of Medical Science · JPUniversity of Basel · CH
Funding
No grant is acknowledged in the PubMed record.
Abstract
Double homeobox 4 (
Indexed as
biology of human developmentdevelopmental biologymolecular biology
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What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.