Evidence map›Paper›PMID 35402751›Full record

ArticleiScience notes2019

QUANTIFICATION OF MITOCHONDRIAL MEMBRANE CURVATURE BY THREE-DIMENSIONAL LOCALIZATION MICROSCOPY.

Matthew Parent, Samuel T Hess

Open access · greenAbstract read
In one paragraph

Article in iScience notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Triclosan disrupts immune cell function by depressing CaToxicology and applied pharmacology · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew ParentDepartment of Physics and Astronomy, University of Maine, Maine, USA.
Samuel T HessDepartment of Physics and Astronomy, University of Maine, Maine, USA.
University of Southern Maine · US

Funding

Genetic Control of Phospholipid Biosynthesis and Muscular DystrophyR01AR054170 · NIAMS · JACKSON LABORATORY · PI COX, GREGORY A. · 2007 to 2016
$4.4M
The Role of the Actin Cytoskeleton and Cholesterol in Influenza Virus AssemblyR15GM094713 · NIGMS · UNIVERSITY OF MAINE ORONO · PI HESS, SAMUEL T · 2010 to 2010
$425k
Mechanism of Association between Influenza Hemagglutinin and the Host Cell Actin CytoskeletonR15GM116002 · NIGMS · UNIVERSITY OF MAINE ORONO · PI HESS, SAMUEL T · 2015 to 2015
$337k
NIAMS NIH HHS R01 AR054170NIGMS NIH HHS R15 GM094713NIGMS NIH HHS R15 GM116002
6 · The paper itself

Abstract

Mitochondrial membrane organization is important for many biological functions, and is implicated in a number of diseases, but conventional microscopy has insufficient resolution to image biologically relevant structures. We present methods to quantify nanoscale membrane curvature using three-dimensional localization-based super-resolution microscopy. Localizations are analyzed using a cluster algorithm followed by principal component analysis to determine local membrane curvature. Results are shown for mitochondria in C2C12 mouse myotubes labeled with Tom20-Dendra2.

Identifiers

PMID35402751
PMCPMC8992009
OpenAlexW2985007151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.