Evidence map›Paper›PMID 35402685›Full record

ArticleSSM - population health2022

Trajectories of cognitive functioning in later life: Disparities by race/ethnicity, educational attainment, sex, and multimorbidity combinations.

Ana R Quiñones, Siting Chen, Corey L Nagel, Anda Botoseneanu, Heather G Allore, Jason T Newsom, Stephen Thielke, Jeffrey Kaye

Open access · goldAbstract read
In one paragraph

Article in SSM - population health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Evidence of APOE4-related brain vulnerabilities in verbal memory systems in midlife women.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
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  7. Article
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  9. Article
  10. Cardiometabolic Multimorbidity and Dementia Onset Among Middle-Aged and Older Adults: Differences by Race/Ethnicity.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Ana R QuiñonesDepartment of Family Medicine, Oregon Health & Science University, USA.
Siting ChenOHSU-PSU School of Public Health, Portland, OR, USA.
Corey L NagelCollege of Nursing, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Anda BotoseneanuDepartment of Health & Human Services, University of Michigan, Dearborn, MI, USA.
Heather G AlloreDepartment of Internal Medicine, Yale University, USA.
Jason T NewsomDepartment of Psychology, Portland State University, Portland, OR, USA.
Stephen ThielkeDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Jeffrey KayeDepartment of Neurology, Oregon Health & Science University, Portland, OR, USA.
Oregon Health & Science University · USPortland State University · USUniversity of Arkansas for Medical Sciences · USUniversity of Michigan · USUniversity of Portland · USUniversity of Washington · USYale University · US

Funding

The National Health and Trends StudyU01AG032947 · NIA · JOHNS HOPKINS UNIVERSITY · PI VICKI A. FREEDMAN, JENNIFER ANN SCHRACK · 2008 to 2026
$169.4M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Yale Alzheimer Disease Research CenterP30AG066508 · NIA · YALE UNIVERSITY · PI STEPHEN M STRITTMATTER · 2020 to 2026
$30.2M
Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
Outreach, Recruitment and Education CoreP30AG008017 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI DODGE, HIROKO HAYAMA · 1990 to 2019
$27.7M
Pilot CoreP30AG024978 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KAYE, JEFFREY A · 2004 to 2023
$9.0M
Multimorbidity Combinations and Dementia Onset Among Race/Ethnic Older AdultsRF1AG058545 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI QUINONES, ANA ROMAN · 2019 to 2019
$3.6M
Individualized Absolute Risk calculator For Persons With Multiple Chronic ConditionsR01AG047891 · NIA · YALE UNIVERSITY · PI ALLORE, HEATHER GWYNN · 2015 to 2017
$990k
NIA NIH HHS P30 AG008017NIA NIH HHS P30 AG021342NIA NIH HHS P30 AG024978NIA NIH HHS P30 AG066508NIA NIH HHS P30 AG066518NIA NIH HHS R01 AG047891NIA NIH HHS RF1 AG058545NIA NIH HHS U01 AG032947
6 · The paper itself

Abstract

Evaluating multimorbidity combinations, racial/ethnic background, educational attainment, and sex associations with age-related cognitive changes is critical to clarifying the health, sociodemographic, and socioeconomic mechanisms associated with cognitive function in later life. Data from the 2011-2018 National Health and Aging Trends Study for respondents aged 65 years and older (N = 10,548, mean age = 77.5) were analyzed using linear mixed effect models. Racial/ethnic differences (mutually-exclusive groups: non-Latino White, non-Latino Black, and Latino) in cognitive trajectories and significant interactions with sex and education (<high school, high school, some college, and ≥ college degree) were evaluated. Models included sex, education, ever covered by Medicaid, coupled status, waist-height ratio, study cohort, and chronic disease category (no diseases; one disease;

Indexed as

Cognitive functionDisparitiesMultimorbidityRace/ethnicity

Identifiers

PMID35402685
PMCPMC8987641
OpenAlexW4223547903

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.