ReviewFrontiers in cardiovascular medicine2022
Ventricular Unloading Using the Impella
Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Impella Versus VA-ECMO in Cardiogenic Shock: An Updated Systematic Review and Meta-Analysis With Exploratory Matched-Cohort Analyses.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Pooled it
- Article
- Management of Spontaneous Coronary Dissection Complicated by Cardiogenic Shock: A Case Report.Clinical case reports · 2026Article
- Perioperative timing of surgically implanted microaxial flow pump support in high-risk coronary artery bypass grafting: a single-center Society of Thoracic Surgeons study.Journal of thoracic disease · 2026Article
- Oral P2YInternational journal of cardiology. Heart & vasculature · 2026Article
- Impella vs. IABP in Non-emergent High-Risk PCI: Outcomes and LVEF Recovery from a Large US EHR Study.Cardiology and therapy · 2026Article
- The Buddy-Wire Technique for Impella RP Placement: A Case Report.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Clinical outcomes of Impella 5+ in acute myocardial infarction-related cardiogenic shock: a retrospective single-center study.Frontiers in cardiovascular medicine · 2026Article
- Case Report: Extracorporeal membrane oxygenation in acute coronary syndrome: a rare case of massive left ventricular thrombus.Frontiers in cardiovascular medicine · 2026Article
- The Hidden Vulnerability: How Underlying SMA Stenosis Turns Routine Intra-Aortic Balloon Pump Support Into Fatal Mesenteric Ischemia.Case reports in critical care · 2026Article
- Clinical outcomes following Impella escalation in cardiogenic shock: a single-centre case series highlighting the gap between haemodynamic improvement and survival.AME case reports · 2026Article
- Cardiovascular Physiology During Mechanical Circulatory Support: Implications for Management and Monitoring.Journal of clinical medicine · 2025Review
- The Role of Impella in Cardiogenic Shock in the Post-DanGer Shock Era.Biomedicines · 2025Review
- Mechanically-foldable axial flow blood pump: response-surface-based structural optimization and hemolytic performance evaluation.Frontiers in physiology · 2025Article
- [Progress in the analysis of hemolysis and coagulation models for interventional micro-axial flow blood pumps].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Review
- Mechanical Circulatory Support in Pediatric Myocarditis: Support Strategies and Outcomes in a Nationally Representative Cohort.JHLT open · 2024Article
- Prolonged Impella 5.0/5.5 support within different pathways of care for cardiogenic shock: the experience of a referral center.Frontiers in cardiovascular medicine · 2024Article
- Patient selection for left ventricular unloading: is lactate the vital piece of the puzzle?Journal of thoracic disease · 2023Article
- Complications and Outcomes of Impella Treatment in Cardiogenic Shock Patients With and Without Acute Myocardial Infarction.Journal of the American Heart Association · 2023Article
- Role of acute mechanical circulatory support devices in cardiogenic shock.Indian journal of thoracic and cardiovascular surgery · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiogenic shock (CS) remains a leading cause of hospital death. However, the use of mechanical circulatory support has fundamentally changed CS management over the last decade and is rapidly increasing. In contrast to extracorporeal membrane oxygenation as well as counterpulsation with an intraaortic balloon pump, ventricular unloading by the Impella™ device actively reduces ventricular volume as well as pressure and augments systemic blood flow at the same time. By improving myocardial oxygen supply and enhancing systemic circulation, the Impella device potentially protects myocardium, facilitates ventricular recovery and may interrupt the shock spiral. So far, the evidence supporting the use of Impella™ in CS patients derives mostly from observational studies, and there is a need for adequate randomized trials. However, the Impella™ device appears a promising technology for management of CS patients. But a profound understanding of the device, its physiologic impact and clinical application are all important when evaluating CS patients for percutaneous circulatory support. This review provides a comprehensive overview of the percutaneous assist device Impella™. Moreover, it highlights in depth the rationale for ventricular unloading in CS and describes practical aspects to optimize care for patients requiring hemodynamic support.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.