Evidence map›Paper›PMID 35402554›Full record

ArticleFrontiers in cardiovascular medicine2022

Association of Left Ventricular Diastolic Dysfunction With Cardiovascular Outcomes in Patients With Pre-dialysis Chronic Kidney Disease: Findings From KNOW-CKD Study.

Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Kook-Hwan Oh, Kyu Hun Choi, Yun Kyu Oh, Seong Kwon Ma, Soo Wan Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sang Heon SuhDepartment of Internal Medicine, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, South Korea.
Tae Ryom OhDepartment of Internal Medicine, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, South Korea.
Hong Sang ChoiDepartment of Internal Medicine, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, South Korea.
Chang Seong KimDepartment of Internal Medicine, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, South Korea.
Eun Hui BaeDepartment of Internal Medicine, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, South Korea.
Kook-Hwan OhDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
Kyu Hun ChoiDepartment of Internal Medicine, College of Medicine, Institute of Kidney Disease Research, Yonsei University, Seoul, South Korea.
Yun Kyu OhDepartment of Internal Medicine, Seoul National University, Seoul, South Korea.
Seong Kwon MaDepartment of Internal Medicine, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, South Korea.
Soo Wan KimDepartment of Internal Medicine, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, South Korea.
Chonnam National University Hospital · KRSeoul National University · KRSeoul National University Hospital · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The impact of left ventricular diastolic dysfunction (LVDD) on cardiovascular (CV) outcomes in patients with pre-dialysis chronic kidney disease (CKD) has been rarely unveiled. We here investigated the association of LVDD with CV outcomes and all-cause mortality in patients with pre-dialysis CKD. Methods: A total of 2,135 patients with pre-dialysis CKD from the Korean Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD) cohort were dichotomized by the absence or presence of LVDD, which was defined as the ratio of the early transmitral blood flow velocity to early diastolic velocity of the mitral annulus ( Results: Cox regression analysis revealed that LVDD was significantly associated with increased risk of composite CV events [adjusted hazard ratio (HR) 2.194, 95% confidence interval (CI) 1.486-3.240] and all-cause mortality (adjusted HR 1.830, 95% CI 1.168-2.869). Restricted cubic splines visualized stringent linear correlations of Conclusion: LVDD is independently associated with adverse CV outcomes and all-cause mortality in patients with pre-dialysis CKD.

Indexed as

all-cause mortalitycardiovascular outcomechronic kidney diseaseheart failureleft ventricular diastolic dysfunction

Identifiers

PMID35402554
PMCPMC8990123
OpenAlexW4220695822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.