Evidence map›Paper›PMID 35402463›Full record

ArticleFrontiers in medicine2022

Computed Tomography Radiomics-Based Prediction of Microvascular Invasion in Hepatocellular Carcinoma.

Wenjun Yao, Shuo Yang, Yaqiong Ge, Wenlong Fan, Li Xiang, Yang Wan, Kangchen Gu, Yan Zhao, Rujing Zha, Junjie Bu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. [Research progress in radiomics based on CT and MRI images for prediction of microvascular invasion in hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Wenjun YaoDepartment of Radiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Shuo YangDepartment of Radiology, Anhui Mental Health Center, Hefei, China.
Yaqiong GeGE Healthcare China, Shanghai, China.
Wenlong FanDepartment of Radiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Li XiangDepartment of Radiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Yang WanDepartment of Hematological Lab, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Kangchen GuDepartment of Radiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Yan ZhaoSchool of Biomedical Engineering, Anhui Medical University, Hefei, China.
Rujing ZhaDepartment of Radiology, Division of Life Science and Medicine, The First Affiliated Hospital of USTC, School of Life Science, University of Science and Technology of China, Hefei, China.
Junjie BuSchool of Biomedical Engineering, Anhui Medical University, Hefei, China.
Anhui Medical University · CNSecond Hospital of Anhui Medical University · CNAnhui Mental Health Center · CNFourth Affiliated Hospital of Anhui Medical University · CNUnited Imaging Healthcare (China) · CNUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Due to the high recurrence rate in hepatocellular carcinoma (HCC) after resection, preoperative prognostic prediction of HCC is important for appropriate patient management. Exploring and developing preoperative diagnostic methods has great clinical value in treating patients with HCC. This study sought to develop and evaluate a novel combined clinical predictive model based on standard triphasic computed tomography (CT) to discriminate microvascular invasion (MVI) in hepatocellular carcinoma (HCC). Methods: The preoperative findings of 82 patients with HCC, including conventional clinical factors, CT imaging findings, and CT texture analysis (TA), were analyzed retrospectively. All included cases were divided into MVI-negative ( Results: We found that tumor diameter and pathological grade were effective clinical predictors in clinical model and 12 radiomics features were effective for MVI prediction of each CT phase. The AUCs of the clinical, plain, artery, venous, and delay models were 0.77 (95% CI: 0.67-0.88), 0.75 (95% CI: 0.64-0.87), 0.79 (95% CI: 0.69-0.89), 0.73 (95% CI: 0.61-0.85), and 0.80 (95% CI: 0.70-0.91), respectively. The novel combined model exhibited the best performance, with an AUC of 0.83 (95% CI: 0.74-0.93). Conclusions: Models derived from triphasic CT can preoperatively predict MVI in patients with HCC. Of the models tested here, the novel combined model was most predictive and could become a useful tool to guide subsequent personalized treatment of HCC.

Indexed as

hepatocellular carcinomamicrovascular invasionnomogramradiomicstriphasic computed tomography

Identifiers

PMID35402463
PMCPMC8987588
OpenAlexW4226139566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.