Evidence map›Paper›PMID 35402415›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Electrochemical Detection of Alzheimer's Disease Biomarker, β-Secretase Enzyme (BACE1), With One-Step Synthesized Reduced Graphene Oxide.

Jhilik Dey, Akanksha Roberts, Subhasis Mahari, Sonu Gandhi, Prem Prakash Tripathi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jhilik DeyCell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Akanksha RobertsDBT-National Institute of Animal Biotechnology (NIAB), Hyderabad, India.
Subhasis MahariDBT-National Institute of Animal Biotechnology (NIAB), Hyderabad, India.
Sonu GandhiDBT-National Institute of Animal Biotechnology (NIAB), Hyderabad, India.
Prem Prakash TripathiCell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
National Institute of Animal Biotechnology · INIndian Institute of Chemical Biology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Secretase1 (BACE1) catalyzes the rate-limiting step in the generation of amyloid-β peptides, that is, the principal component involved in the pathology of Alzheimer's disease (AD). Recent research studies show correlation between blood and cerebrospinal fluid (CSF) levels of BACE1 with the pathophysiology of AD. In this study, we report one-step synthesized reduced graphene oxide (rGO), activated

Indexed as

Alzheimer’s diseaseBACE1diagnosticgraphene oxideimmunosensor

Identifiers

PMID35402415
PMCPMC8987718
OpenAlexW4220992928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.