ReviewFrontiers in bioengineering and biotechnology2022
Surface Modification Techniques to Produce Micro/Nano-scale Topographies on Ti-Based Implant Surfaces for Improved Osseointegration.
Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nanoscale Morphologies on the Surface of 3D-Printed Titanium Implants for Improved Osseointegration: A Systematic Review of the Literature.International journal of nanomedicine · 2023Pooled it
- Surface Engineering in Materials (2nd Edition).Materials (Basel, Switzerland) · 2026Article
- Multiscale Interface Engineering for Orthopedic and Dental Implants: A Review.Journal of functional biomaterials · 2026Review
- Surface Modification of Polyetheretherketone (PEEK) via Femtosecond Laser Microprocessing for Enhanced Bioactivity: A Preliminary Study.Bioengineering (Basel, Switzerland) · 2025Article
- Evaluating the Efficacy of a Novel Titanium Cage System in ALIF and LLIF: A Retrospective Clinical and Radiographic Analysis.Journal of clinical medicine · 2025Article
- Preparation of high-quality pure titanium SLA surface and evaluation of its physicochemical and biological properties - in vitro experiments.BMC oral health · 2025Article
- Lateral Spacing of TiOBiomimetics (Basel, Switzerland) · 2025Article
- The Masquelet technique triggers the formation of a network involving LncRNA, circRNA, miRNA, and mRNA during bone repair.Annals of medicine · 2024Article
- Nanotechnology in healthcare, and its safety and environmental risks.Journal of nanobiotechnology · 2024Review
- Effects of restraint stress and surface treatments on the stability of titanium dental implant osseointegration in dogs: An in vivo comparative study.Journal of Taibah University Medical Sciences · 2024Article
- Enhanced antibacterial activity and superior biocompatibility of cobalt-deposited titanium discs for possible use in implant dentistry.iScience · 2024Article
- Effect of Er:YAG Pulsed Laser-Deposited Hydroxyapatite Film on Titanium Implants on M2 Macrophage Polarization In Vitro and Osteogenesis In Vivo.International journal of molecular sciences · 2023Article
- Synergistic Enhancement of Protein Recruitment and Retention via Implant Surface Microtopography and Superhydrophilicity in a Computational Fluid Dynamics Model.International journal of molecular sciences · 2023Article
- Bioglass and Vitamin D3 Coatings for Titanium Implants: Osseointegration and Corrosion Protection.Biomedicines · 2023Article
- The current status of stimuli-responsive nanotechnologies on orthopedic titanium implant surfaces.Journal of nanobiotechnology · 2023Review
- Plasma Electrolytic Oxidation for Dental Implant Surface Treatment.Sovremennye tekhnologii v meditsine · 2023Article
- Layer-by-layer assembly of procyanidin and collagen promotes mesenchymal stem cell proliferation and osteogenic differentiationRegenerative biomaterials · 2023Article
- Cold physical plasma treatment optimization for improved bone allograft processing.Frontiers in bioengineering and biotechnology · 2023Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titanium and titanium alloys are used as artificial bone substitutes due to the good mechanical properties and biocompatibility, and are widely applied in the treatment of bone defects in clinic. However, Pure titanium has stress shielding effect on bone, and the effect of titanium-based materials on promoting bone healing is not significant. To solve this problem, several studies have proposed that the surface of titanium-based implants can be modified to generate micro or nano structures and improve mechanical properties, which will have positive effects on bone healing. This article reviews the application and characteristics of several titanium processing methods, and explores the effects of different technologies on the surface characteristics, mechanical properties, cell behavior and osseointegration. The future research prospects in this field and the characteristics of ideal titanium-based implants are proposed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.