Evidence map›Paper›PMID 35402273›Full record

ArticleFrontiers in oncology2022

Experimental Comparison of Fiducial Markers Used in Proton Therapy: Study of Different Imaging Modalities and Proton Fluence Perturbations Measured With CMOS Pixel Sensors.

Claire-Anne Reidel, Felix Horst, Christoph Schuy, Oliver Jäkel, Swantje Ecker, Katrin Henkner, Stephan Brons, Marco Durante, Uli Weber

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Universal Fiducial Markers for Multi-Modal Radiotherapy.International journal of particle therapy · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Claire-Anne ReidelBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany.
Felix HorstBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany.
Christoph SchuyBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany.
Oliver JäkelDivision of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Swantje EckerHeidelberg Ion Beam Therapy Center (HIT), Heidelberg, Germany.
Katrin HenknerHeidelberg Ion Beam Therapy Center (HIT), Heidelberg, Germany.
Stephan BronsHeidelberg Ion Beam Therapy Center (HIT), Heidelberg, Germany.
Marco DuranteBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany.
Uli WeberBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany.
GSI Helmholtz Centre for Heavy Ion Research · DEHeidelberger Institut für Radioonkologie · DETechnical University of Darmstadt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fiducial markers are used for image guidance to verify the correct positioning of the target for the case of tumors that can suffer interfractional motion during proton therapy. The markers should be visible on daily imaging, but at the same time, they should produce minimal streak artifacts in the CT scans for treatment planning and induce only slight dose perturbations during particle therapy. In this work, these three criteria were experimentally investigated at the Heidelberg Ion Beam Therapy Center. Several small fiducial markers with different geometries and materials (gold, platinum, and carbon-coated ZrO

Indexed as

CMOS pixel sensordose perturbationfiducial markerimage guidanceMonte Carlo simulationproton therapystreak artifacts

Identifiers

PMID35402273
PMCPMC8990863
OpenAlexW4220922718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.