Evidence map›Paper›PMID 35402166›Full record

ArticleSchizophrenia research. Cognition2022

Cognitive remediation in schizophrenia: What happens after 10 years?

Mariachiara Buonocore, Marco Spangaro, Margherita Bechi, Stefania Trezzani, Rachele Terragni, Francesca Martini, Giulia Agostoni, Federica Cocchi, Federica Cuoco, Carmelo Guglielmino and 2 more

Abstract read
In one paragraph

Article in Schizophrenia research. Cognition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mariachiara BuonocoreDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Marco SpangaroDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Margherita BechiDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Stefania TrezzaniVita-Salute San Raffaele University, Milan, Italy.
Rachele TerragniVita-Salute San Raffaele University, Milan, Italy.
Francesca MartiniDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Giulia AgostoniVita-Salute San Raffaele University, Milan, Italy.
Federica CocchiDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Federica CuocoDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Carmelo GuglielminoDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Marta BosiaDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Roberto CavallaroDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive Remediation Therapy (CRT) represents the gold standard treatment for cognitive impairment in schizophrenia, but the permanence of its effects over time have been poorly investigated. Our study aims to evaluate long lasting cognitive and functional effects of CRT together with standard rehabilitation interventions (SRT) in a group of patients diagnosed with schizophrenia, 10 years after the end of the treatment. Forty patients, previously included in a 5-year follow-up study evaluating the effects of CRT combined with SRT, were revalued 10 years after the complete of the intervention. Results revealed that cognitive and functional improvements of combined CRT/SRT interventions are still preserved 10 years after the end of the treatments, with the only exception of psychomotor speed and coordination cognitive subdomain. Moreover, investigating persistence of the influence of SRT, patients that underwent a shorter SRT following CRT (six months vs one year) showed worsened processing speed abilities. This is the first study confirming that cognitive and functional improvements of joint CRT/SRT interventions are still conserved 10 years after the end of the treatments. Preliminary datas suggest that a longer SRT following CRT may lead to significant benefits, in terms of cognitive gains, in patients affected by schizophrenia.

Indexed as

Daily functioningFollow-upNeurocognitionQuality of lifeRehabilitationSchizophrenia

Identifiers

PMID35402166
PMCPMC8983434

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.