Evidence map›Paper›PMID 35401926›Full record

ArticleOxidative medicine and cellular longevity2022

Chitosan Oligosaccharides Alleviate H

Ziwei Yang, Wenli Hong, K Zheng, Jingyuan Feng, Chuan Hu, Jun Tan, Zhisheng Zhong, Yuehui Zheng

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ziwei YangJiangxi Medical College, Nanchang University, Nanchang 330006, China.
Wenli HongHealth Science Center, Shenzhen University, Shenzhen 518000, China.
K ZhengMedical College, Shantou University, Shantou 515041, China.
Jingyuan FengJiangxi Medical College, Nanchang University, Nanchang 330006, China.
Chuan HuJiangxi Medical College, Nanchang University, Nanchang 330006, China.
Jun TanReproductive Medicine Center, Jiangxi Maternal and Child Health Hospital, Nanchang 330006, China.ORCID https://orcid.org/0000-0001-9080-7534
Zhisheng ZhongJiangxi Provincial Key Laboratory of Reproductive Physiology and Pathology, Nanchang 330031, China.ORCID https://orcid.org/0000-0003-2944-9680
Yuehui ZhengJiangxi Provincial Key Laboratory of Reproductive Physiology and Pathology, Nanchang 330031, China.ORCID https://orcid.org/0000-0002-2345-7893
Jiangxi Maternal and Child Health Hospital · CNNanchang University · CNShantou University · CNShenzhen University Health Science Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oocyte maturation disorder and decreased quality are the main causes of infertility in women, and granulosa cells (GCs) provide the only microenvironment for oocyte maturation through autocrine and paracrine signaling by steroid hormones and growth factors. However, chronic inflammation and oxidative stress caused by ovarian hypoxia are the largest contributors to ovarian aging and GC dysfunction. Therefore, the amelioration of chronic inflammation and oxidative stress is expected to be a pivotal method to improve GC function and oocyte quality. In this study, we detected the protective effect of chitosan oligosaccharides (COS), on hydrogen peroxide- (H

Indexed as

ChitosanHydrogen PeroxideFemaleGlutathioneGranulosa CellsHumansHypoxia-Inducible Factor 1, alpha SubunitInflammationOligosaccharidesSignal TransductionVascular Endothelial Growth Factor AChitosanGlutathioneHydrogen PeroxideHypoxia-Inducible Factor 1, alpha SubunitOligosaccharidesVascular Endothelial Growth Factor A

Identifiers

PMID35401926
PMCPMC8993563
OpenAlexW4220892310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.