Evidence map›Paper›PMID 35401915›Full record

ArticleThe Neurohospitalist2022

Anti-NMDAr Encephalitis and COVID-19 in a Patient With Systemic pANCA-Vasculitis and Recurrent Varicella Zoster Infection.

João Moura, Sara Duarte, Ana Sardoeira, João Neves-Maia, Joana Damásio, Ricardo Taipa, Paula Carneiro, Esmeralda Neves, Ana Campar, Ernestina Santos

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The Neurohospitalist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

João MouraDepartment of Neurology, Centro Hospitalar Universitário do Porto, Porto, Portugal.ORCID https://orcid.org/0000-0002-4212-906X
Sara DuarteDepartment of Neurology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Ana SardoeiraDepartment of Neurology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
João Neves-MaiaDepartment of Internal Medicine, Centro Hospitalar Unniversitário do Porto, Porto, Portugal.
Joana DamásioDepartment of Neurology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Ricardo TaipaDepartment of Neurology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Paula CarneiroImmunology Department, Centro Hospitalar Universitário do Porto, Porto, Portugal.ORCID https://orcid.org/0000-0001-8760-4015
Esmeralda NevesImmunology Department, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Ana CamparDepartment of Internal Medicine, Centro Hospitalar Unniversitário do Porto, Porto, Portugal.
Ernestina SantosDepartment of Neurology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Centro Hospitalar do Porto · PTUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: There is a complex interplay between systemic autoimmunity, immunosuppression, and infections. Any or all of these can result in neurologic manifestations, requiring diligence on the part of neurologists. Case report: We herein report a case of a patient on immunosuppressive treatment for a vasculitis that resulted in zoster meningoencephalitis. This was further complicated by the development of anti-NMDAr encephalitis, the etiology of which is undetermined and further discussed in this paper. The patient eventually developed COVID-19 during hospitalization, succumbing to the respiratory infection. Conclusion: This case emphasizes that post-infectious autoimmune disorders are becoming increasingly recognized and that they should still be considered in patients who are on immunosuppression. Practitioners should be aware of the complex relationship between autoimmunity and immunosuppression and consider both throughout the disease course.

Indexed as

anti-NMDArCOVID-19encephalitisvaricella zostervasculitis

Identifiers

PMID35401915
PMCPMC8977756
OpenAlexW4205202507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.