ArticleDisease markers2022
Tissue-Type Plasminogen Activator-Inhibitor Complex as an Early Predictor of Septic Shock: A Retrospective, Single-Center Study.
Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- TM and t-PAIC may be possible biomarkers to predict postoperative infection after cardiac surgery with cardiopulmonary bypass.Journal of cardiothoracic surgery · 2026Observational
- The diagnostic and prognostic value of sTM, t-PAIC, and NLRP3 in ICU patients with sepsis.BMC infectious diseases · 2026Article
- Distinct patterns of endothelial response to endotoxin in aged mice as compared to young mice.GeroScience · 2026Article
- Construction of a nomogram prediction model for prolonged ICU length of stay in patients with sepsis-induced coagulopathy.European journal of medical research · 2026Article
- Explainable machine learning model for predicting septic shock in critically sepsis patients based on coagulation indexes: A multicenter cohort study.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- The value of thrombus markers applied in patients with respiratory failure.Journal of medical biochemistry · 2025Article
- Screening and Application of DNA Aptamers for Heparin-Binding Protein.Molecules (Basel, Switzerland) · 2024Article
- Alterations of Hemostatic Molecular Markers During Acute Large Vessel Occlusion Stroke.Journal of the American Heart Association · 2024Article
- Clinical value of TAT, PIC and t-PAIC as predictive markers for severe sepsis in pediatric patients.Frontiers in pediatrics · 2024Article
- Atrial fibrillation episode status and incidence of coronary slow flow: A propensity score-matched analysis.Frontiers in cardiovascular medicine · 2023Article
- Preoperative hypoalbuminemia as a prognosis indicator in patients with surgical sepsis and septic shock.Saudi journal of anaesthesiaArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sepsis can progress to septic shock and death, and identifying biomarkers of this progression may permit timely intervention to prevent it. This study explored whether levels of tissue-type plasminogen activator-inhibitor complex (t-PAIC) in serum can predict septic shock early. Methods: We retrospectively analyzed 311 sepsis patients who had been admitted to the intensive care unit (ICU) at our tertiary care hospital between May 2018 and April 2021, and we divided them into those who progressed to septic shock ( Results: After propensity score matching to generate two equal groups of 108 patients, we found that serum t-PAIC was significantly higher in septic shock patients. Uni- and multivariate logistic regression identified t-PAIC as an independent risk factor for septic shock (OR 1.14, 95% CI 1.09-1.19, Conclusions: Serum levels of t-PAIC may be an independent risk factor for septic shock, and they may correlate with the severity of such shock.
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