Evidence map›Paper›PMID 35401822›Full record

ArticleTheranostics2022

Assay design for unambiguous identification and quantification of circulating pathogen-derived peptide biomarkers.

Qingbo Shu, Shan Liu, Tonino Alonzi, Sylvia M LaCourse, Dhiraj Kumar Singh, Duran Bao, Dalton Wamalwa, Li Jiang, Christopher J Lyon, Grace John-Stewart and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Qingbo ShuCenter for Cellular and Molecular Diagnostics, Department of Biochemistry and Molecular Biology, School of Medicine, Tulane University, New Orleans, Louisiana, USA.
Shan LiuSichuan Provincial Key Laboratory for Human Disease Gene Study, Department of Medical Genetics, Department of Laboratory medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
Tonino AlonziTranslational Research Unit, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, Rome, Italy.
Sylvia M LaCourseDepartments of Medicine, Division of Allergy and Infectious Diseases, and Global Health, University of Washington, Seattle, USA.
Dhiraj Kumar SinghSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Duran BaoCenter for Cellular and Molecular Diagnostics, Department of Biochemistry and Molecular Biology, School of Medicine, Tulane University, New Orleans, Louisiana, USA.
Dalton WamalwaDepartment of Pediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Li JiangSichuan Provincial Key Laboratory for Human Disease Gene Study, Department of Medical Genetics, Department of Laboratory medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
Christopher J LyonCenter for Cellular and Molecular Diagnostics, Department of Biochemistry and Molecular Biology, School of Medicine, Tulane University, New Orleans, Louisiana, USA.
Grace John-StewartDepartments of Medicine, Division of Allergy and Infectious Diseases, and Global Health, University of Washington, Seattle, USA.
Deepak KaushalSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Delia GolettiTranslational Research Unit, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, Rome, Italy.
Tony HuCenter for Cellular and Molecular Diagnostics, Department of Biochemistry and Molecular Biology, School of Medicine, Tulane University, New Orleans, Louisiana, USA.
Tulane University · USTexas Biomedical Research Institute · USIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITUniversity of Nairobi · KE

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Urgent Versus Post-Stabilization ART in HIV+ Children with Severe Co-infectionsR01HD023412 · NICHD · UNIVERSITY OF WASHINGTON · PI Grace C. John-Stewart, DALTON CHEKOKO WAMALWA · 1987 to 2026
$12.2M
Direct quantitation of the circulating Mtb-peptidome for pediatric TB managementR01HD090927 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI Christopher J Lyon, Charles DeBeaux Mitchell · 2017 to 2026
$4.5M
M. tuberculosis exosome detection for pediatric TB diagnosisR01AI162152 · NIAID · UNIVERSITY OF WASHINGTON · PI LACOURSE, SYLVIA · 2021 to 2025
$3.3M
Quantification of Circulating Antigens for Pediatric TB Diagnosis andTreatment MonitoringR01AI122932 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI HU, TONY Y. · 2016 to 2019
$1.8M
Real-time Detection of Active TB in HIV Exposed Children on CustomizedNanotrapR01AI113725 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI LABAER, JOSHUA · 2015 to 2018
$1.6M
Impact of maternal HIV on Mycobacterium tuberculosis infection among peripartum women and their infantsK23AI120793 · NIAID · UNIVERSITY OF WASHINGTON · PI LACOURSE, SYLVIA · 2016 to 2020
$910k
NanoDisk-MS measured Mtb antigen peptides for TB diagnosis and treatment monitoring in HIV-infected childrenR21AI143341 · NIAID · UNIVERSITY OF WASHINGTON · PI LACOURSE, SYLVIA · 2019 to 2020
$443k
Multiplexed quantification of circulating peptidomic signatures for EBOLA early diagnosisR21AI126361 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI LABAER, JOSHUA · 2017 to 2018
$373k
NIAID NIH HHS K23 AI120793NIAID NIH HHS R01 AI113725NIAID NIH HHS R01 AI122932NIAID NIH HHS R01 AI162152NIAID NIH HHS R21 AI126361NIAID NIH HHS R21 AI143341NICHD NIH HHS R01 HD023412NICHD NIH HHS R01 HD090927NIH HHS P51 OD011133
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mycobacterium tuberculosisTuberculosisAnimalsBiomarkersPeptidesSensitivity and SpecificityBiomarkersPeptidesimmunoprecipitationmass spectrometryMRMpeptide biomarkertuberculosis

Identifiers

PMID35401822
PMCPMC8965485
OpenAlexW4225728594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.