Evidence map›Paper›PMID 35401813›Full record

ArticleTheranostics2022

Plaque-targeted, proteolysis-resistant, activatable and MRI-visible nano-GLP-1 receptor agonist targets smooth muscle cell differentiation in atherosclerosis.

Andrei Maiseyeu, Lin Di, Anastasia Ravodina, Alma Barajas-Espinosa, Atsushi Sakamoto, Alice Chaplin, Jixin Zhong, Huiyun Gao, Matthew Mignery, Navneet Narula and 2 more

Open access · goldFull text read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  10. TargetedImmunotherapy advances · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Andrei MaiseyeuCase Western Reserve University, Cleveland, OH.
Lin DiCase Western Reserve University, Cleveland, OH.
Anastasia RavodinaCase Western Reserve University, Cleveland, OH.
Alma Barajas-EspinosaDorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH.
Atsushi SakamotoCVPath Institute, Inc., Gaithersburg, MD.
Alice ChaplinCase Western Reserve University, Cleveland, OH.
Jixin ZhongCase Western Reserve University, Cleveland, OH.
Huiyun GaoCase Western Reserve University, Cleveland, OH.
Matthew MigneryCase Western Reserve University, Cleveland, OH.
Navneet NarulaNYU Langone Medical Center, New York, NY.
Aloke V FinnUniversity of Maryland, Baltimore, MD.
Sanjay RajagopalanCase Western Reserve University, Cleveland, OH.
Case Western Reserve University · USUniversity of Maryland, Baltimore · USCVPath Institute · USNYU Langone Health · USThe Ohio State University · US

Funding

Probing Cardiovascular Actions of GLP-1 Using NanoparticlesR01HL130516 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MAISEYEU, ANDREI · 2016 to 2020
$1.9M
Non-racemic metabolic biomaterials for HFpEFR01HL155450 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI MAISEYEU, ANDREI · 2021 to 2024
$1.6M
NHLBI NIH HHS R01 HL130516NHLBI NIH HHS R01 HL155450
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AtherosclerosisGlucagon-Like Peptide-1 Receptor AgonistsPlaque, AtheroscleroticAnimalsCell DifferentiationInflammationLiraglutideMagnetic Resonance ImagingMiceMice, Inbred C57BLMice, Knockout, ApoEMuscle, SmoothProteolysisRNA, MessengerGlucagon-Like Peptide-1 Receptor AgonistsLiraglutideRNA, MessengeratherosclerosisGLP-1MRInanomedicinesmooth muscle cells

Identifiers

PMID35401813
PMCPMC8965488
OpenAlexW4225341310

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.