Evidence map›Paper›PMID 35401802›Full record

ArticleExperimental and therapeutic medicine2022

Association of vitamin D receptor gene TaqI polymorphism with Alzheimer's disease in a Southeastern European Caucasian population.

Efthimios Dimitrakis, Martha-Spyridoula Katsarou, Maria Lagiou, Vasiliki Papastefanopoulou, Evangelia Stanitsa, Demetrios A Spandidos, Aristidis Tsatsakis, Socratis Papageorgiou, Paraskevi Moutsatsou, Katerina Antoniou and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Role of Calcitriol and Vitamin D Receptor (International journal of molecular sciences · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Efthimios DimitrakisResearch Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15784 Athens, Greece.
Martha-Spyridoula KatsarouResearch Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15784 Athens, Greece.
Maria LagiouResearch Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15784 Athens, Greece.
Vasiliki PapastefanopoulouDepartment of Clinical Biochemistry, University General Hospital 'ATTIKON', 12462 Athens, Greece.
Evangelia StanitsaSecond Department of Neurology, University General Hospital 'ATTIKON', 12462 Athens, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece.
Aristidis TsatsakisDepartment of Forensic Sciences and Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Socratis PapageorgiouSecond Department of Neurology, University General Hospital 'ATTIKON', 12462 Athens, Greece.
Paraskevi MoutsatsouDepartment of Clinical Biochemistry, University General Hospital 'ATTIKON', 12462 Athens, Greece.
Katerina AntoniouDepartment of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece.
Christos KroupisDepartment of Clinical Biochemistry, University General Hospital 'ATTIKON', 12462 Athens, Greece.
Nikolaos DrakoulisResearch Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15784 Athens, Greece.
University General Hospital Attikon · GRNational and Kapodistrian University of Athens · GRUniversity of Crete · GRUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of vitamin D in Alzheimer's Disease (AD) has been studied over the past years. The results from numerous studies have indicated that the molecular pathways involved in the development of AD are closely related to the molecular pathways of the mechanisms of action of vitamin D. However, only a limited number of studies have described the key role of vitamin D receptor (VDR) in the regulation of the functions of vitamin D and the potential effect of single nucleotide polymorphisms (SNPs) of the

Indexed as

Alzheimer's diseaseMMSEpolymorphismTaqIvitamin D receptor

Identifiers

PMID35401802
PMCPMC8988159
OpenAlexW4220770921

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.