Evidence map›Paper›PMID 35401766›Full record

ArticleJournal of exercise science and fitness2022

Effects of one-year once-weekly high-intensity interval training on body adiposity and liver fat in adults with central obesity: Study protocol for a randomized controlled trial.

Edwin C Chin, Chit K Leung, Danny J Yu, Angus P Yu, Joshua K Bernal, Christopher W Lai, Derwin K C Chan, Heidi H Ngai, Patrick S H Yung, Chi H Lee and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of exercise science and fitness, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03912272 (Effectiveness of Long-term Low-frequency High-Intensity Interval Training), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03912272 nacompletednot on this map

Effectiveness of Long-term Low-frequency High-Intensity Interval Training (HIIT) to Improve Body Adiposity and Liver Fat in Adults With Central Obesity: A Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2019 to 2024Enrolled160ConditionsNon-Alcoholic Fatty Liver Disease, Central ObesityArmsHigh-intensity Interval Training, Usual Care Control
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Edwin C ChinDivision of Kinesiology, School of Public Health, The University of Hong Kong, Hong Kong, China.
Chit K LeungDivision of Kinesiology, School of Public Health, The University of Hong Kong, Hong Kong, China.
Danny J YuDivision of Kinesiology, School of Public Health, The University of Hong Kong, Hong Kong, China.
Angus P YuDivision of Kinesiology, School of Public Health, The University of Hong Kong, Hong Kong, China.
Joshua K BernalDivision of Kinesiology, School of Public Health, The University of Hong Kong, Hong Kong, China.
Christopher W LaiSingapore Institute of Technology, Singapore.
Derwin K C ChanDepartment of Early Childhood Education, The Education University of Hong Kong, Hong Kong, China.
Heidi H NgaiDietetic Clinic, School of Professional and Continuing Education, The University of Hong Kong, Hong Kong, China.
Patrick S H YungDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Chi H LeeDepartment of Medicine, The University of Hong Kong, Hong Kong, China.
Daniel Y FongSchool of Nursing, The University of Hong Kong, Hong Kong, China.
Shelley E KeatingSchool of Human Movement and Nutrition Sciences, The University of Queensland, Australia.
Jeff S CoombesSchool of Human Movement and Nutrition Sciences, The University of Queensland, Australia.
Parco M SiuDivision of Kinesiology, School of Public Health, The University of Hong Kong, Hong Kong, China.
University of Hong Kong · HKThe University of Queensland · AUChinese University of Hong Kong · HKEducation University of Hong Kong · HKSingapore Institute of Technology · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to examine the effects of one-year, once-weekly high-intensity interval training (HIIT) on body adiposity and liver fat in adults with central obesity. Methods: One-hundred and twenty adults aged 18-60 years with central obesity (body mass index ≥25, waist circumference ≥90 cm for men and ≥80 cm for women). This is an assessor-blinded randomized controlled trial. Participants will be randomly assigned to the HIIT group or the usual care control group. Each HIIT session will consist of 4 × 4-min bouts at 85%-95% maximal heart rate, interspersed with 3-min bouts at 50%-70% maximal heart rate. The HIIT group will complete one session per week for 12 months, whereas the usual care control group will receive health education. The primary outcomes of this study are total body adiposity and intrahepatic triglyceride content. The secondary outcomes include abdominal visceral adipose tissue, subcutaneous adipose tissue, body mass index, waist circumference, hip circumference, cardiorespiratory fitness, lean body mass, bone mineral density, blood pressure, fasting blood glucose, insulin, triglycerides, glycated hemoglobin, cholesterol profile, liver function enzymes, medications, adherence to exercise, adverse events, quality of life, and mental health. Outcome measure will be conducted at baseline, 12 months (post-intervention), and 24 months (one-year follow-up). Impact of the project: This study will explore the benefits of long-term once-weekly HIIT with a follow-up period to assess its effectiveness, adherence, and sustainability. We expect this intervention will enhance the practical suitability of HIIT in inactive adults with central obesity, and provide insights on low-frequency HIIT as a novel exercise option for the management of patients with central obesity and liver fat. Trial registration: ClinicalTrials.gov (NCT03912272) registered on 11 April 2019.

Indexed as

Abdominal obesityHepatic steatosisHigh-intensity exerciseHIITMAFLD

Identifiers

PMID35401766
PMCPMC8943247
OpenAlexW4220934047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.