Evidence map›Paper›PMID 35401744›Full record

ArticleJournal of oncology2022

Clinical Value of Serum miRNA in Patients with Acute Promyelocytic Leukemia.

Bei Zhang, Zhixin Pei, Hongxia Wang, Junjun Bai, Junjie Wang, Yingxin Zhao, Mei Jiang, Huimin Wu, Qinglin Song

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Bei ZhangDepartment of Hematology, Jiaozuo People's Hospital, Jiaozuo 454000, China.
Zhixin PeiDepartment of Hematology, Jiaozuo People's Hospital, Jiaozuo 454000, China.
Hongxia WangDepartment of Hematology, Jiaozuo People's Hospital, Jiaozuo 454000, China.
Junjun BaiDepartment of Hematology, Jiaozuo People's Hospital, Jiaozuo 454000, China.
Junjie WangDepartment of Hematology, Jiaozuo People's Hospital, Jiaozuo 454000, China.
Yingxin ZhaoDepartment of Hematology, Jiaozuo People's Hospital, Jiaozuo 454000, China.
Mei JiangDepartment of Nuclear Medicine, The Second Affiliated Hospital of Henan Polytechnic University, Jiaozuo 454000, China.
Huimin WuDepartment of Hematology, Jiaozuo People's Hospital, Jiaozuo 454000, China.
Qinglin SongDepartment of Hematology, Jiaozuo People's Hospital, Jiaozuo 454000, China.ORCID https://orcid.org/0000-0002-3234-2465
Jiaozuo University · CNHenan Polytechnic University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the clinical value of specific miRNA in patients with acute promyelocytic leukemia. Methods: 129 patients with acute promyelocytic leukemia diagnosed in our hospital from January 2015 to January 2020 were selected as the observation group. At the same time, 74 patients with nonacute promyelocytic leukemia who underwent bone marrow aspiration were included as the control group. The expression levels of miR-126-5p and miR-13, different characteristic parameters, and prognosis were compared between the two groups, and the clinical significance of miR-126-5p and miR-13 in acute promyelocytic leukemia was analyzed. Results: The expression of miR-126-5p (12.31 ± 2.25 versus 17.30 ± 3.28) and miR-13 (16.05 ± 3.47 versus 21.66 ± 2.18) in the observation group was significantly lower than that in the control group ( Conclusion: Serum miR-126-5p and miR-13 are closely related to the prognosis of patients with acute promyelocytic leukemia. Serum miR-126-5p and miR-13 can be used as reliable indexes to predict the prognosis of patients.

Identifiers

PMID35401744
PMCPMC8993542
OpenAlexW4220863702

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.