Evidence map›Paper›PMID 35401541›Full record

ArticleFrontiers in immunology2022

Deletion of the Natural Killer Cell Receptor NKG2C Encoding

Hannes Vietzen, Bernd Döhler, Thuong Hien Tran, Caner Süsal, Philip F Halloran, Farsad Eskandary, Carsten T Herz, Katharina A Mayer, Nicolas Kozakowski, Markus Wahrmann and 4 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Novel Aspects of Immunogenetics and Post-Transplant Events in Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  6. Natural Killer Cell Presence in Antibody-Mediated Rejection.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  7. The Transplant Bellwether: Endothelial Cells in Antibody-Mediated Rejection.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Review
  8. Article
  9. Article
  10. Inhibitory NKG2AFrontiers in immunology · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Hannes VietzenCenter for Virology, Medical University of Vienna, Vienna, Austria.
Bernd DöhlerInstitute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Thuong Hien TranInstitute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Caner SüsalInstitute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Philip F HalloranAlberta Transplant Applied Genomics Centre (ATAGC), University of Alberta, Edmonton, AB, Canada.
Farsad EskandaryDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Carsten T HerzDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Katharina A MayerDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Nicolas KozakowskiDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Markus WahrmannDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Sarah ElyDepartment of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Susanne HaindlDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Elisabeth Puchhammer-StöcklCenter for Virology, Medical University of Vienna, Vienna, Austria.
Georg A BöhmigDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATHeidelberg University · DEUniversity Hospital Heidelberg · DEUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells may contribute to antibody-mediated rejection (ABMR) of renal allografts. The role of distinct NK cell subsets in this specific context, such as NK cells expressing the activating receptor NKG2C, is unknown. Our aim was to investigate whether

Indexed as

Kidney TransplantationCross-Sectional StudiesGraft RejectionHumansIsoantibodiesNK Cell Lectin-Like Receptor Subfamily CNK Cell Lectin-Like Receptor Subfamily DReceptors, Natural Killer CellIsoantibodiesKLRC2 protein, humanNK Cell Lectin-Like Receptor Subfamily CNK Cell Lectin-Like Receptor Subfamily DReceptors, Natural Killer Cellantibody-mediated rejectiondonor-specific antibodykidney transplantationmicrovascular inflammationnatural killer cellNKG2C receptor

Identifiers

PMID35401541
PMCPMC8987017
OpenAlexW4220880857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.