Evidence map›Paper›PMID 35401531›Full record

ArticleFrontiers in immunology2022

Induced Synthesis of Mycolactone Restores the Pathogenesis of

Emily Strong, Bryan Hart, Jia Wang, Maria Gonzalez Orozco, Sunhee Lee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. The dual role of the microbiome in chronic wound management.Cell communication and signaling : CCS · 2026
    Review
  2. Life (Basel, Switzerland) · 2025
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Emily StrongDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Bryan HartHuman Vaccine Institute, Duke University, Durham, NC, United States.
Jia WangDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Maria Gonzalez OrozcoDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Sunhee LeeDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
The University of Texas Medical Branch at Galveston · USDuke University · US

Funding

Modulation of Host Cell Environment by Mycobacterial PE/PPE ProteinsR01AI127711 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI LEE, SUNHEE, PORCELLI, STEVEN A · 2017 to 2021
$2.8M
NIAID NIH HHS R01 AI127711
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ToxinsBuruli UlcerMycobacterium ulceransAnimalsMacrolidesMiceBacterial ToxinsMacrolidesmycolactoneapoptosisBuruli ulcercytotoxicityhost–microbe interactionmacrophagesmycobacteriamycolactonenecrosis

Identifiers

PMID35401531
PMCPMC8988146
OpenAlexW4220793096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.