Evidence map›Paper›PMID 35401417›Full record

ArticleFrontiers in neurology2022

Lobar Cerebral Microbleeds Are Associated With Cognitive Decline in Patients With Type 2 Diabetes Mellitus.

Pengfei Shao, Hengheng Xu, Xiaoning Sheng, Ruomeng Qin, Junyi Ma, Yishan Luo, Allan Lee, Lin Shi, Lili Huang, Yue Cheng and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Frequency of anti-GQ1b IgG antibody in Miller Fisher syndrome: a Chinese single center study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Pengfei ShaoDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Hengheng XuDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Xiaoning ShengDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Ruomeng QinDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Junyi MaDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Yishan LuoBrainNow Research Institute, Shenzhen, China.
Allan LeeBrainNow Research Institute, Shenzhen, China.
Lin ShiBrainNow Research Institute, Shenzhen, China.
Lili HuangDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Yue ChengDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Hui ZhaoDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Yun XuDepartment of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Nanjing University · CNNanjing Drum Tower Hospital · CNChinese University of Hong Kong · CNJiangsu Province Blood Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Combined the number, volume, and location of cerebral microbleeds (CMBs), this study aimed to explore the different features of CMBs and their correlation with cognitive ability in patients with type 2 diabetes mellitus (T2DM). Methods: This study recruited 95 patients with T2DM and 80 healthy control (HC) individuals. AccuBrain Results: After adjusting for several variables, the total volume of CMBs (OR = 0.332, 95%CI: 0.133-0.825, and Conclusions: Lobar CMBs was related with cognitive impairment in patients with T2DM and might be a potential early warning signal. Compared with the counting analysis, the quantitative method offered a more sensitive and objective measurement for studying imaging features of CMBs.

Indexed as

cerebral microbleeds (CMBs)cognitive impairmentMRIquantitative methodtype 2 diabetes mellitus

Identifiers

PMID35401417
PMCPMC8990891
OpenAlexW4220922923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.