Evidence map›Paper›PMID 35401411›Full record

ArticleFrontiers in neurology2022

Fully Automatic Classification of Brain Atrophy on NCCT Images in Cerebral Small Vessel Disease: A Pilot Study Using Deep Learning Models.

Jincheng Wang, Sijie Chen, Hui Liang, Yilei Zhao, Ziqi Xu, Wenbo Xiao, Tingting Zhang, Renjie Ji, Tao Chen, Bing Xiong and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jincheng WangDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Sijie ChenState Key Laboratory of Medical Neurobiology and Collaborative Innovation Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China.
Hui LiangDepartment of Neurology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yilei ZhaoDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Ziqi XuDepartment of Neurology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Wenbo XiaoDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Tingting ZhangDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Renjie JiDepartment of Neurology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Tao ChenDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Bing XiongDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Feng ChenDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jun YangTaimei Medical Technology, Shanghai, China.
Haiyan LouDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Zhejiang University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Brain atrophy is an important imaging characteristic of cerebral small vascular disease (CSVD). Our study explores the linear measurement application on CT images of CSVD patients and develops a fully automatic brain atrophy classification model. The second aim was to compare it with the end-to-end Convolutional Neural Networks (CNNs) model. Methods: A total of 385 subjects such as 107 no-atrophy brain, 185 mild atrophy, and 93 severe atrophy were collected and randomly separated into training set ( Results: Automated measurement of linear measurements and cerebral sulci widening achieved moderate to almost perfect agreement with manual annotation. In two-type atrophy classification, area under the curves (AUCs) of the 2D model and 3D model were 0.953 and 0.941 with no significant difference ( Conclusion: We provide a model composed of different modules that can classify CSVD-related brain atrophy on CT images automatically, using linear measurement. It has similar performance and better interpretability than the end-to-end CNNs model and may prove advantageous in the clinical setting.

Indexed as

automated classificationbrain atrophycerebral small vessel diseasecomputed tomographyconvolutional neural networksdeep learninglinear measurement

Identifiers

PMID35401411
PMCPMC8989434
OpenAlexW4221015615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.