Evidence map›Paper›PMID 35401409›Full record

ArticleFrontiers in neurology2022

Thoracic Excursion Is a Biomarker for Evaluating Respiratory Function in Amyotrophic Lateral Sclerosis.

Naohiko Iguchi, Tomoo Mano, Naoki Iwasa, Maki Ozaki, Nanami Yamada, Naoya Kikutsuji, Akira Kido, Kazuma Sugie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Naohiko IguchiDepartment of Neurology, Nara Medical University, Kashihara, Japan.
Tomoo ManoDepartment of Neurology, Nara Medical University, Kashihara, Japan.
Naoki IwasaDepartment of Neurology, Nara Medical University, Kashihara, Japan.
Maki OzakiDepartment of Neurology, Nara Medical University, Kashihara, Japan.
Nanami YamadaDepartment of Neurology, Nara Medical University, Kashihara, Japan.
Naoya KikutsujiDepartment of Neurology, Nara Medical University, Kashihara, Japan.
Akira KidoDepartment of Rehabilitation Medicine, Nara Medical University, Kashihara, Japan.
Kazuma SugieDepartment of Neurology, Nara Medical University, Kashihara, Japan.
Nara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the usefulness of thoracic excursion as a biomarker in patients with amyotrophic lateral sclerosis (ALS). Methods: We measured the forced the vital capacity (FVC), thoracic excursion, baseline-to-peak diaphragmatic compound muscle action potential (DCMAP) amplitude, diaphragm thickness at full inspiration (DTfi), Medical Research Council (MRC) sum score for muscle strength, and arterial partial pressures of oxygen and carbon dioxide and administered the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) and modified Medical Research Council (mMRC) Dyspnea Scale. The test-retest reliability of thoracic excursion was determined. Results and Conclusions: Thirty-four patients with ALS and 26 age- and sex-matched healthy participants were enrolled. Thoracic excursion measurement had excellent test-retest reliability (intraclass coefficient: 0.974). Thoracic excursion was more strongly correlated with FVC (

Indexed as

amyotrophic lateral sclerosisbiomarkerpulmonary function testrespiratory functionthoracic excursion

Identifiers

PMID35401409
PMCPMC8984343
OpenAlexW4220777058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.