Evidence map›Paper›PMID 35401245›Full record

ArticleFrontiers in psychiatry2022

Attitudes Toward a Pre-authorized Concealed Opioid Taper: A Qualitative Analysis of Patient and Clinician Perspectives.

Theresa Bedford, Nkaku Kisaalita, Nathaniel R Haycock, C Daniel Mullins, Thelma Wright, Michele Curatolo, Lynette Hamlin, Luana Colloca

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Theresa Bedford711 Human Performance Wing, En Route Care, Wright Patterson Air Force Base, OH, United States.
Nkaku KisaalitaMental Health Service Line, Orlando Veterans Affairs Healthcare System, Orlando, FL, United States.
Nathaniel R HaycockDepartment of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, MD, United States.
C Daniel MullinsDepartment of Pharmaceutical Health Services Research, School of Pharmacy, University of Maryland, Baltimore, MD, United States.
Thelma WrightDepartment of Anesthesiology, School of Medicine, University of Maryland, Baltimore, MD, United States.
Michele CuratoloDepartment of Anesthesiology & Pain Medicine, School of Medicine, University of Washington, Seattle, WA, United States.
Lynette HamlinUniformed Services University of the Health Sciences, Graduate School of Nursing, Bethesda, MD, United States.
Luana CollocaDepartment of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, MD, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Standard opioid tapers tend to be associated with increased patient anxiety and higher pain ratings. Pre-authorized concealed opioid reductions may minimize expectations such as fear of increased pain due to the reduction of opioids and, prolong analgesic benefits in experimental settings. We recently observed that patients and clinicians are open to concealed opioid tapering. However, little is known about the "why" behind their attitudes. Based on this lack of data, we analyzed qualitative responses to survey questions on patients' and clinicians' acceptance of a concealed opioid reduction for chronic pain. Seventy-four patients with a history of high dose opioid therapy and 49 clinicians completed a web-based questionnaire with open-ended questions examining responses to two hypothetical clinical trials comparing a concealed opioid reduction pre-authorized by patients vs. standard tapering. We used content analysis based on qualitative descriptive methodology to analyze comments from the patients and clinicians. Five themes were identified: informed consent; anxiety; safety; support; and ignorance is bliss, or not. These themes highlight the overall positive attitudes toward concealed opioid tapers. Our findings reinforce the importance of patient-centered care and are expected to inform the design of clinical trials from both the patient and clinician perspective. This qualitative study presents patients' and clinicians' attitudes toward hypothetical scenarios for a trial of pre-authorized reduction of opioids. The findings indicate positive attitudes and the relevance of engaging patients with effective decision-making processes.

Indexed as

chronic painconcealed (hidden) administrationopioid taperingplacebo effectsqualitative descriptive

Identifiers

PMID35401245
PMCPMC8987573

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.