Evidence map›Paper›PMID 35401087›Full record

ArticleFrontiers in neuroscience2022

Unique Finding of a Primary Central Nervous System Neuroendocrine Carcinoma in a 5-Year-Old Child: A Case Report.

Natalia Stepien, Christine Haberler, Sarah Theurer, Maria-Theresa Schmook, Carola Lütgendorf-Caucig, Leonhard Müllauer, Johannes Gojo, Amedeo A Azizi, Thomas Czech, Irene Slavc and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Natalia StepienDepartment of Pediatric and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Christine HaberlerDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria.
Sarah TheurerInstitute of Pathology, University of Duisburg-Essen, Essen, Germany.
Maria-Theresa SchmookDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Carola Lütgendorf-CaucigMedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Leonhard MüllauerDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Johannes GojoDepartment of Pediatric and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Amedeo A AziziDepartment of Pediatric and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Thomas CzechDepartment of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Irene SlavcDepartment of Pediatric and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Andreas PeyrlDepartment of Pediatric and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroendocrine tumors (NETs) are rare neoplasms predominantly arising in the gastrointestinal-tract or the lungs of adults. To date, only ten cases of primary central nervous system (CNS) NETs have been reported, with just three of them describing a neuroendocrine carcinoma (NECA) and none occurring in a child. We report on a previously healthy 5-year-old boy, who presented with headaches, nausea and vomiting, and was diagnosed with a left cerebellar solid mass with a cystic component. After gross-total resection, histology revealed a neuroendocrine carcinoma. Molecular analysis of the tumor tissue showed a

Indexed as

neuroendocrine carcinoma (NEC)neuroendocrine tumorspediatric brain tumorprimary CNS tumorrare entities

Identifiers

PMID35401087
PMCPMC8984181

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.