Evidence map›Paper›PMID 35401038›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2022

Progression of AFP SCORE is a Preoperative Predictive Factor of Microvascular Invasion in Selected Patients Meeting Liver Transplantation Criteria for Hepatocellular Carcinoma.

Astrid Herrero, Lucile Boivineau, Gianluca Cassese, Eric Assenat, Benjamin Riviere, Stéphanie Faure, José Ursic Bedoya, Fabrizio Panaro, Boris Guiu, Francis Navarro and 1 more

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. An exploratory nomogram model withJournal of gastrointestinal oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Astrid HerreroDepartment of Digestive Surgery and Liver Transplantation, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Lucile BoivineauLiver Transplantation Unit, Department of Hepatology, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Gianluca CasseseDepartment of Digestive Surgery and Liver Transplantation, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Eric AssenatDepartment of Digestive Oncology, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Benjamin RiviereDepartment of Pathology, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Stéphanie FaureLiver Transplantation Unit, Department of Hepatology, Montpellier University Hospital, University of Montpellier, Montpellier, France.
José Ursic BedoyaLiver Transplantation Unit, Department of Hepatology, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Fabrizio PanaroDepartment of Digestive Surgery and Liver Transplantation, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Boris GuiuDepartment of Digestive Imaging, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Francis NavarroDepartment of Digestive Surgery and Liver Transplantation, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Georges-Philippe PageauxLiver Transplantation Unit, Department of Hepatology, Montpellier University Hospital, University of Montpellier, Montpellier, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microvascular invasion (MVI) is one of the main prognostic factors of hepatocellular carcinoma (HCC) after liver transplantation (LT), but its occurrence is unpredictable before surgery. The alpha fetoprotein (AFP) model (composite score including size, number, AFP), currently used in France, defines the selection criteria for LT. This study's aim was to evaluate the preoperative predictive value of AFP SCORE progression on MVI and overall survival during the waiting period for LT. Data regarding LT recipients for HCC from 2007 to 2015 were retrospectively collected from a single institutional database. Among 159 collected cases, 34 patients progressed according to AFP SCORE from diagnosis until LT. MVI was shown to be an independent histopathological prognostic factor according to Cox regression and competing risk analysis in our cohort. AFP SCORE progression was the only preoperative predictive factor of MVI (OR = 10.79 [2.35-49.4];

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsLiver Transplantationalpha-FetoproteinsHumansNeoplasm InvasivenessNeoplasm Recurrence, LocalRetrospective StudiesRisk Factorsalpha-Fetoproteinsdelta AFP scorehepatocellular carcinomaliver transplantationmicrovascular invasionrecurrence

Identifiers

PMID35401038
PMCPMC8983829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.