ReviewVascular health and risk management2022
The Klippel-Trénaunay Syndrome in 2022: Unravelling Its Genetic and Molecular Profile and Its Link to the Limb Overgrowth Syndromes.
Review in Vascular health and risk management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Pulmonary Embolism as the Initial Presentation of Klippel-Trénaunay Syndrome.JACC. Case reports · 2026Article
- Bloom Syndrome Presenting With Early-Onset Myelodysplastic Syndrome and Triple Overlapping Vascular Neurocutaneous Phenotypes: A Case Report.Clinical case reports · 2026Article
- Targeted therapy guided by photon-counting computed tomography in Klippel-Trénaunay syndrome.Journal of vascular surgery. Venous and lymphatic disorders · 2026Article
- Long-term treatment of Klippel-Trenaunay syndrome in an adult patient using multimodal laser therapy.JAAD case reports · 2026Article
- Klippel-trenaunay syndrome in a child with coexisting lymphangioma, vascular insufficiency, and multiple soft tissue swellings: a case report.Oxford medical case reports · 2026Article
- Multidisciplinary approach to Klippel-Trenaunay syndrome: a case report.Annals of medicine and surgery (2012) · 2025Article
- Genetic basis and imaging findings of neurofibromatosis 1 and other somatic overgrowth disorders.Skeletal radiology · 2025Review
- Therapeutic applications of natural products in the management of venous diseases: a comprehensive review.Inflammopharmacology · 2025Review
- Scrotal hemangioma misdiagnosed as a malignant tumor in Klippel-Trénaunay syndrome: a case report and review of the literature.Journal of vascular surgery cases and innovative techniques · 2024Article
- Pathophysiology in Brain Arteriovenous Malformations: Focus on Endothelial Dysfunctions and Endothelial-to-Mesenchymal Transition.Biomedicines · 2024Review
- SomaticPediatric investigation · 2024Article
- Value of the short time inversion recovery sequence of magnetic resonance imaging in the staging of Klippel-Trenaunay syndrome complicated with lymphedema.Journal of vascular surgery. Venous and lymphatic disorders · 2024Article
- Radiation-Induced Angiosarcoma in a Patient With Klippel-Trenaunay Syndrome: A Case Report.Eplasty · 2024Article
- Klippel-Trenaunay syndrome and chiari I malformation. A case report and systematic review of the literature.Brain & spine · 2024Article
- Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases.Genome medicine · 2023Article
- Epidemiology of the disorders of the Pik3ca-related overgrowth spectrum (Pros).European journal of human genetics : EJHG · 2023Article
- Parkes Weber syndrome: a rare cause of foot drop.BMJ case reports · 2023Article
- Klippel-Trenaunay Syndrome, Segmental/Focal Overgrowth Malformations: A Review.Children (Basel, Switzerland) · 2023Review
- A case of chyluria with nephrotic-range proteinuria caused by lymphatic malformation, leading to a diagnosis of Klippel-Trenaunay syndrome.CEN case reports · 2023Article
- A Rare Case of Klippel-Trénaunay Syndrome.Cureus · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Klippel-Trénaunay syndrome is an unusual syndrome of vascular and dermatologic manifestation in which patients demonstrate hemihypertrophy of the soft tissue and bones of one limb, cutaneous haemangiomas and varicosities in anatomically abnormal positions. Described in 1900 by two French physicians, the etiology remained unclear until recently, when evidence emerged that there was a genetic basis for this sporadic disorder. Genes that encoded pathological angiogenic factors and caused vascular dysmorphogenesis, explaining the molecular bases of this syndrome, were identified. Several angiogenic genes were identified but one gene, the
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.