Evidence map›Paper›PMID 35400990›Full record

ArticleMolecular vision2022

Association of

Manoel Vinicius Rocha Araki, Yuri Carvalho Oiamore Silva, Thiago Adalton Rosa Rodrigues, Flavia Fialho Bajano, Bruno Batista de Souza, Fernando Ferreira Costa, Vital Paulino Costa, Mônica Barbosa de Melo, José Paulo Cabral de Vasconcellos

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Molecular vision, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Polymorphic variants ofInternational journal of ophthalmology · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Manoel Vinicius Rocha ArakiDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas - UNICAMP, Campinas - SP, Brazil.
Yuri Carvalho Oiamore SilvaLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering, University of Campinas - UNICAMP, Campinas - SP, Brazil.
Thiago Adalton Rosa RodriguesLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering, University of Campinas - UNICAMP, Campinas - SP, Brazil.
Flavia Fialho BajanoLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering, University of Campinas - UNICAMP, Campinas - SP, Brazil.
Bruno Batista de SouzaLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering, University of Campinas - UNICAMP, Campinas - SP, Brazil.
Fernando Ferreira CostaHematology and Hemotherapy Center, University of Campinas, Campinas - SP, Brazil.
Vital Paulino CostaDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas - UNICAMP, Campinas - SP, Brazil.
Mônica Barbosa de MeloLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering, University of Campinas - UNICAMP, Campinas - SP, Brazil.
José Paulo Cabral de VasconcellosDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas - UNICAMP, Campinas - SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Glaucoma is the world's leading cause of irreversible blindness, with primary open-angle glaucoma (POAG) being the most prevalent subtype. In recent years, there have been advances in knowledge about the genetics involved in POAG, but genetic studies in admixed populations, such as Brazilians, are still rare. This study aimed to evaluate the association of single nucleotide variants (SNV) of the Methods: A cross-sectional association study with 1,009 subjects (505 patients with POAG and 504 controls) was performed. Participants underwent a comprehensive ocular examination, including the need for surgical procedures for intraocular pressure control. Genotyping of SNVs was performed using the TaqMan genotyping assay. Results: SNV rs9913911 of Conclusions: In a Brazilian population sample, there was an association identified between SNV rs9913911 (

Indexed as

GlaucomaGlaucoma, Open-AngleATP Binding Cassette Transporter 1BrazilCross-Sectional StudiesGenetic Predisposition to DiseaseGenotypeHumansIntraocular PressureNerve Tissue ProteinsPolymorphism, Single NucleotideABCA1 protein, humanATP Binding Cassette Transporter 1GAS7 protein, humanNerve Tissue Proteins

Identifiers

PMID35400990
PMCPMC8942454
OpenAlexW4225881026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.