Evidence map›Paper›PMID 35400813›Full record

ArticleJournal of clinical biochemistry and nutrition2022

Induction of mucosal healing by intensive granulocyte/monocyte adsorptive apheresis (GMA) without use of corticosteroids in patients with ulcerative colitis: long-term remission maintenance after induction by GMA and efficacy of GMA re-treatment upon relapse.

Takumi Fukuchi, Kousaku Kawashima, Hideaki Koga, Ran Utsunomiya, Kohei Sugiyama, Keiji Shimazu, Takaaki Eguchi, Shunji Ishihara

Abstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Takumi FukuchiDepartment of Gastroenterology and Hepatology, Iseikai Hospital, Osaka, Japan.
Kousaku KawashimaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, Enya-cho 89-1, Izumo 693-8501, Japan.
Hideaki KogaDepartment of Gastroenterology and Hepatology, Iseikai Hospital, Osaka, Japan.
Ran UtsunomiyaDepartment of Gastroenterology and Hepatology, Iseikai Hospital, Osaka, Japan.
Kohei SugiyamaDepartment of Gastroenterology and Hepatology, Iseikai Hospital, Osaka, Japan.
Keiji ShimazuDepartment of Nephrology, Saiseikai Nakatsu Hospital, Osaka, Japan.
Takaaki EguchiDepartment of Gastroenterology and Hepatology, Saiseikai Nakatsu Hospital, Osaka, Japan.
Shunji IshiharaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, Enya-cho 89-1, Izumo 693-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the long-term maintenance rate after inducing remission by intensive granulocyte/monocyte adsorptive apheresis (GMA) without use of corticosteroids (CS) and GMA re-treatment efficacy in the same patients upon relapse with ulcerative colitis. Patients who achieved clinical remission and mucosal healing (MH) by first-time intensive GMA (first GMA) without CS were enrolled. The cumulative non-relapse survival rate up to week 156 was calculated. Patients with relapse during the maintenance period underwent second-time intensive GMA (second GMA) without CS. Clinical remission and MH rates following second GMA were compared to those following first GMA in the same patients. Of the 84 patients enrolled, 78 were followed until week 156 and 34 demonstrated relapse. The cumulative non-relapse survival rate by week 156 was 56.4%. Clinical remission and MH rates after second GMA did not differ from those after first GMA in the same patients (week 6: clinical remission, 100% vs 88.4%,

Indexed as

intensive GMAremission maintenancere-treatmentulcerative colitis

Identifiers

PMID35400813
PMCPMC8921725

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.