ArticleHematology, transfusion and cell therapy2023
Pulmonary embolism in pediatrics: A 10-year experience from a tertiary center in Brazil.
Article in Hematology, transfusion and cell therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Epidemiological characteristics of pulmonary thromboembolism in children: a systematic review and meta-analysis.BMJ open · 2026Pooled it
- Septic pulmonary embolism in Somali children: a retrospective study from a tertiary hospital.Frontiers in pediatrics · 2026Article
- A global survey on practice changes and barriers to the use of direct oral anticoagulants in children.Blood advances · 2025Article
- High- and intermediate-risk pulmonary embolism in pediatric tertiary care centers in the Netherlands.Research and practice in thrombosis and haemostasis · 2025Article
- Elevated risk of dyspnea in pediatric patients three months after pulmonary embolism.Respiratory medicine · 2025Article
- Radiological findings in septic pulmonary embolism with detection of gram-negative and gram-positive bacteria in microbiological culture: A rare pediatric case report.Radiology case reports · 2024Article
- Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition.Frontiers in cardiovascular medicine · 2023Article
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4 authors.
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Abstract
introductionAlthough still rare, pulmonary embolism (PE) in children has been increasing over the years. Data regarding this group of patients are still sparse, which contributes to the lack of standardized prophylaxis protocols and the misdiagnosis. This study aimed to determine the incidence of pediatric PE at a Brazilian tertiary hospital, describe clinical characteristics and identify possible risk factors. We also analyzed the diagnosis and management of PE.
methodsThis was a retrospective review of tertiary Brazilian single-center data of all pediatric patients (0 - 18 years) with acute PE, diagnosed radiologically, from September 2009 to May 2019.
resultsThe incidence of PE was 3.3 cases per 10,000 hospitalized children. All the twenty-three cases had some risk factor identified and sixteen of them (69.5%) had more than one risk factor. The most important were central venous catheter (39.1%), malignancy (34.8%) and recent surgery (34.8%). Among the children with identifiable symptoms (69.5%), the most common was dyspnea (56.2%). Only one patient did not receive antithrombotic therapy because of the high bleeding risk and most patients (70.6%) were treated for 3 to 6 months. Among the nineteen patients alive at the end of the six-month follow-up, ten (52.6%) repeated the PE image control. Seven of them (70.0%) had complete or partial resolution of the thrombosis and none had worsening images.
conclusionOur lower incidence than that of the current literature may reflect underdiagnosis due to low suspicion of PE. At least one risk factor was identified in all patients, which emphasizes the importance of increasing awareness of high-risk children.
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