Observational studyStroke2022
Internal Carotid Artery Tortuosity: Impact on Mechanical Thrombectomy.
Observational study in Stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02251665 (National Cerebral and Cardiovascular Center), which is not on this map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
National Cerebral and Cardiovascular Center (NCVC) Stroke Registry
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Is endovascular treatment still good for acute ischemic stroke in the elderly? A meta-analysis of observational studies in the last decade.Frontiers in neuroscience · 2023Pooled it
- Tmax Mismatch Ratio to Identify Intracranial Atherosclerotic Stenosis-Related Large-Vessel Occlusion Before Endovascular Therapy.Journal of the American Heart Association · 2023Trial
- Intracranial Arterial Dolichoectasia in Spontaneous Intracerebral Hemorrhage: A Retrospective Cross-Sectional Study of Morphometric Features and Cerebral Small Vessel Disease.Journal of clinical medicine · 2026Article
- Diving MCA and First-Pass Effect: A Subgroup Analysis From the ARISE II Study.Stroke (Hoboken, N.J.) · 2026Article
- Predictors and a Nomogram for Parenchymal Hematoma After Endovascular Thrombectomy in Large Core Ischemic Stroke.CNS neuroscience & therapeutics · 2026Article
- Vascular geometry characterization for AI-based endovascular navigation.International journal of computer assisted radiology and surgery · 2026Article
- Sex-Based Efficacy of Endovascular Thrombectomy Techniques in LVO Stroke: A Multicenter Registry Analysis.Stroke · 2026Article
- Feasibility of Using Angioscopy to Visualize the Internal Vessel Wall of the Internal Carotid Artery.Clinical neuroradiology · 2026Article
- Suitability for Transcarotid Transcatheter Aortic Valve Replacement in the Japanese Population.JACC. Asia · 2026Article
- Carotid Artery Stenting Outcomes in Comprehensive Stroke Hospitals (CASSH): A Prospective Multicenter Study.Stroke (Hoboken, N.J.) · 2026Article
- Prevalence and Clinical Characteristics of Isolated Intraventricular Hemorrhage.Cerebrovascular diseases extra · 2026Article
- Prognostic value of intracranial vascular tortuosity in thrombectomy for distal vessel occlusion.European stroke journal · 2026Article
- Impact of cavernous internal carotid artery tortuosity on technical and clinical outcomes in mechanical thrombectomy for acute ischemic stroke: a single-center retrospective study.Frontiers in neurology · 2026Article
- Prediction of catheter navigation difficulty during mechanical thrombectomy using CTA-based carotid siphon morphometry.Frontiers in medical technology · 2026Article
- Predictors of distal embolization during thrombectomy for anterior circulation large vessel bifurcation occlusion stroke.Journal of neurointerventional surgery · 2025Article
- Adverse events and failures with Cerenovus CEREGLIDE 71 Intermediate Catheter: An analytic review of the FDA MAUDE database.Journal of cerebrovascular and endovascular neurosurgery · 2025Article
- Impact of Carotid Artery Tortuosity on Technical Aspects of Endovascular Thrombectomy in a Newly Established Thrombectomy-Capable Stroke Center.Clinics and practice · 2025Article
- Navigating severe vascular tortuosity and cervical carotid loop management in stroke thrombectomy: A case report and review of the literature.Journal of cerebrovascular and endovascular neurosurgery · 2025Article
- Investigation of thrombectomy technique for M2 occlusion based on the M1-M2 bifurcation angle.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- The NeVa Net stent-retriever - initial report of 20 cases from two high volume centres.Acta neurochirurgica · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough tortuosity of the internal carotid artery (ICA) can pose a significant challenge when performing mechanical thrombectomy, few studies have examined the impact of ICA tortuosity on mechanical thrombectomy outcomes.
methodsIn a registry-based hospital cohort, consecutive patients with anterior circulation stroke in whom mechanical thrombectomy was attempted were divided into 2 groups: those with tortuosity in the extracranial or cavernous ICA (tortuous group) and those without (nontortuous group). The extracranial ICA tortuosity was defined as the presence of coiling or kinking. The cavernous ICA tortuosity was defined by the posterior deflection of the posterior genu or the shape resembling Simmons-type catheter. Outcomes included first pass effect (FPE; extended Thrombolysis in Cerebral Infarction score 2c/3 after first pass), favorable outcome (3-month modified Rankin Scale score of 0-2), and intracranial hemorrhage.
resultsOf 370 patients, 124 were in the tortuous group (extracranial ICA tortuosity, 35; cavernous ICA tortuosity, 70; tortuosity at both sites, 19). The tortuous group showed a higher proportion of women and atrial fibrillation than the nontortuous group. FPE was less frequently achieved in the tortuous group than the nontortuous group (21% versus 39%; adjusted odds ratio, 0.45 [95% CI, 0.26-0.77]). ICA tortuosity was independently associated with the longer time from puncture to extended Thrombolysis in Cerebral Infarction ≥2b reperfusion (β=23.19 [95% CI, 13.44-32.94]). Favorable outcome was similar between groups (46% versus 48%;
conclusionsICA tortuosity was independently associated with reduced likelihood of FPE and increased risk of postmechanical thrombectomy intracranial hemorrhage. REGISTRATION: URL: https://www. CLINICALTRIALS: gov; Unique identifier: NCT02251665.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.