Evidence map›Paper›PMID 35400054›Full record

ArticleFrontiers in public health2022

The Incidence and Characteristics of Perinatal Stroke in Beijing: A Multicenter Study.

Qianqian Xia, Zhao Yang, Yao Xie, Ying Zhu, Zixin Yang, Mingyan Hei, Yingxue Ding, Weijing Kong, Limin Kang, Shengnan Yang and 40 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. [A multicenter study of neonatal stroke in Shenzhen, China].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  6. Review
  7. Hemorrhagic stroke in children.Journal of central nervous system disease · 2024
    Review
  8. Advances in the Diagnosis and Treatment of Pediatric Arterial Ischemic Stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors at 15 institutions in 1 country.

Qianqian XiaPediatric Department, Peking University First Hospital, Beijing, China.
Zhao YangPediatric Department, Peking University First Hospital, Beijing, China.
Yao XiePediatric Department, Peking University First Hospital, Beijing, China.
Ying ZhuPediatric Department, Peking University First Hospital, Beijing, China.
Zixin YangBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Mingyan HeiBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Yingxue DingBeijing Friendship Hospital, Capital Medical University, Beijing, China.
Weijing KongBeijing Friendship Hospital, Capital Medical University, Beijing, China.
Limin KangDepartment of Neonatology, Children's Hospital, Capital Institute of Pediatrics, Beijing, China.
Shengnan YangDepartment of Neonatology, Children's Hospital, Capital Institute of Pediatrics, Beijing, China.
Yabo MeiNeonatal Intensive Care Unit of Faculty of Pediatrics, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Zhichun FengNeonatal Intensive Care Unit of Faculty of Pediatrics, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Li ZhangPediatric Department, Haidian Maternal and Child Health Hospital, Beijing, China.
Yanzhe LeiPediatric Department, Haidian Maternal and Child Health Hospital, Beijing, China.
Ping WangDepartment of Neonatology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
Jingyu DongPediatric Department, Tongzhou Maternal and Child Health Hospital, Beijing, China.
Li YangPediatric Department, Tongzhou Maternal and Child Health Hospital, Beijing, China.
Jun JuPediatric Department, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Hesheng ChangPediatric Department, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Shina ZhanPediatric Department, Shunyi Maternal and Children's Hospital of Beijing Children's Hospital, Beijing, China.
Jinqian YuPediatric Department, Shunyi Maternal and Children's Hospital of Beijing Children's Hospital, Beijing, China.
Peng ZhangPediatric Department, Beijing Miyun Maternal and Child Health Hospital, Beijing, China.
Ran WangPediatric Department, Beijing Miyun Maternal and Child Health Hospital, Beijing, China.
Hui GuoPediatric Department, Fengtai Maternal and Child Health Hospital, Beijing, China.
Xinli LiuPediatric Department, Fengtai Maternal and Child Health Hospital, Beijing, China.
Huaqing TanPediatric Department, Beijing Daxing Maternal and Child Care Hospital, Beijing, China.
Yakun LiuPediatric Department, Beijing Daxing Maternal and Child Care Hospital, Beijing, China.
Zhenzong ZhangPediatric Department, The First Hospital of Fangshan, Beijing, China.
Lixia ZhenPediatric Department, The First Hospital of Fangshan, Beijing, China.
Jinting YanPediatric Department, Beijing Mentougou Hospital, Beijing, China.
Zhan LiuPediatric Department, Beijing Mentougou Hospital, Beijing, China.
Chunxia YangPediatric Department, Changping Women and Children Health Care Hospital, Beijing, China.
Qingqing WangPediatric Department, Changping Women and Children Health Care Hospital, Beijing, China.
Jinfeng WangBeijing Pinggu Maternal and Child Health Hospital, Beijing, China.
Lifang SunBeijing Pinggu Maternal and Child Health Hospital, Beijing, China.
Huihui ZengPediatric Department, Huairou Maternal and Child Health Care Hospital, Beijing, China.
Jing LiPediatric Department, Huairou Maternal and Child Health Care Hospital, Beijing, China.
Wenwen QuDepartment of Pediatrics, Peking University Shougang Hospital and Capital Medical University, Beijing, China.
Xuemei WangDepartment of Pediatrics, Peking University Shougang Hospital and Capital Medical University, Beijing, China.
Guiying LiuDepartment of Pediatrics, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xi YangDepartment of Pediatrics, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xinxin LiuPediatric Department, Fifth Medical Center of Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Xuefeng ZhangPediatric Department, Fifth Medical Center of Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Xiaojing XuPediatric Department, The First Hospital of Tsinghua University, Beijing, China.
Yanan GuPediatric Department, The First Hospital of Tsinghua University, Beijing, China.
Hui LongDepartment of Pediatrics, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Li ZhangDepartment of Pediatrics, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Lili LiuPediatric Department, Peking University First Hospital, Beijing, China.
Zezhong TangPediatric Department, Peking University First Hospital, Beijing, China.
Xinlin HouPediatric Department, Peking University First Hospital, Beijing, China.
Capital Medical University · CNPeking University · CNBeijing Obstetrics and Gynecology Hospital · CNChinese People's Liberation Army · CNBeijing Children’s Hospital · CNHainan Maternal and Child Health Hospital · CNBeijing Chuiyangliu Hospital · CNBeijing Fengtai Hospital · CNBeijing Hua Xin Hospital · CNChildren's Hospital of Capital Institute of Pediatrics · CNChongqing Maternal and Child Health Hospital · CNPeking University First Hospital · CNShanghai Changning Maternity and Infant Health Hospital · CNBeijing Anzhen Hospital · CNPeking University Shougang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the incidence, risk factors, and clinical characteristics of perinatal stroke in Beijing. Methods: This multicenter prospective study included all the live births from 17 representative maternal delivery hospitals in Beijing from March 1, 2019 to February 29, 2020. Neonates with a stroke were assigned to the study group. Clinical data, including general information, clinical manifestations, and risk factors, were collected. Up until 18 months after birth, neonates were routinely assessed according to the Ages and Stages Questionnaire (ASQ) and/or the Bayley scale. Statistical analysis was done using the chi-squared, Outcomes: In total, 27 cases were identified and the incidence of perinatal stroke in Beijing was 1/2,660 live births, including 1/5,985 for ischemic stroke and 1/4,788 for hemorrhagic stroke. Seventeen cases (62.96%) of acute symptomatic stroke and convulsions within 72 h (10 cases, 37.04%) were the most common presentations. Ten patients showed no neurological symptoms and were found to have had a stroke through routine cranial ultrasonography after being hospitalized for non-neurological diseases. The risk factors include primiparity, placental or uterine abruption/acute chorioamnionitis, intrauterine distress, asphyxia, and severe infection. In the study group, 11.1% (3/27) of patients had adverse neurodevelopmental outcomes. The patients in the study group had lower scores for the ASQ than those in the control group in the communication, gross, and fine motor dimensions. Conclusion: The incidence of perinatal stroke in Beijing was consistent with that in other countries. Routine neuroimaging of infants with risk factors may enable identification of asymptomatic strokes in more patients. Patients who have suffered from a stroke may have neurological sequelae; therefore, early detection, treatment, and regular follow-ups are beneficial for improving their recovery outcomes.

Indexed as

PlacentaStrokeFemaleHumansIncidenceInfantInfant, NewbornPregnancyProspective StudiesRisk Factorsclinical characteristicsdiagnosisincidenceneonatal strokeprognosis

Identifiers

PMID35400054
PMCPMC8987304
OpenAlexW4220712510

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.