Evidence map›Paper›PMID 35399937›Full record

ArticleFrontiers in endocrinology2022

Yan He, Yinan Li, Jianan Zhang, Linan Chen, Jing Li, Min Zhang, Qiu Zhang, Ying Lu, Jun Jiang, Xiaolong Zhang and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Functional Roles of Furin in Cardio-Cerebrovascular Diseases.ACS pharmacology & translational science · 2024
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Yan HeDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Yinan LiDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Jianan ZhangDepartment of Chronic Disease, Taicang Center for Disease Control and Prevention, Suzhou, China.
Linan ChenDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Jing LiDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Min ZhangDepartment of Central Office, Suzhou National New and Hi-Tech Industrial Development Zone Center for Disease Control and Prevention, Suzhou, China.
Qiu ZhangDepartment of Chronic Disease, Gusu Center for Disease Control and Prevention, Suzhou, China.
Ying LuDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Jun JiangDepartment of Tuberculosis Control, Suzhou Center for Disease Control and Prevention, Suzhou, China.
Xiaolong ZhangDepartment of Tuberculosis Control, Suzhou Center for Disease Control and Prevention, Suzhou, China.
Jianwei HuDepartment of Central Office, Maternal and Child Health Bureau of Kunshan, Suzhou, China.
Yi DingDepartment of Preventive Medicine, College of Clinical Medicine, Suzhou Vocational Health College, Suzhou, China.
Mingzhi ZhangDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Hao PengDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Soochow University · CNChinese Center For Disease Control and Prevention · CNSuzhou Vocational Health College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Furin has been associated with diabetes but the underlying mechanisms are unclear. As a mediator linking fixed genome and dynamic environment, DNA methylation of its coding gene Methods: DNA methylation levels in Results: Among the 1836 participants free of diabetes at baseline, 109 (5.94%) participants developed diabetes during the average of 4 years of follow-up. Hypermethylation at two of the eight CpG sites assayed in the Conclusions: These results suggested that the hypermethylation levels in

Indexed as

Diabetes MellitusDNA MethylationFurinPromoter Regions, GeneticAdultCohort StudiesHumansFurinFURIN protein, humanChinesediabetesDNA methylationfurinprospective observational study

Identifiers

PMID35399937
PMCPMC8990793
OpenAlexW4225992056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.