Evidence map›Paper›PMID 35399846›Full record

SynthesisJournal of healthcare engineering2022

Acyclovir Combined with Naloxone in the Treatment of Viral Encephalitis: A Meta-Analysis.

Wei Wang, Qing Zhao, Qifan Zhang

RetractedOpen access · hybridAbstract readMeta-AnalysisRetracted Publication
In one paragraph

Synthesis in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wei WangDepartment of Neurology, People's Hospital of Ningxia Hui Autonomous Region, Yinchuang, Ningxia Hui Autonomous Region 750002, China.
Qing ZhaoDepartment of Neurology, People's Hospital of Ningxia Hui Autonomous Region, Yinchuang, Ningxia Hui Autonomous Region 750002, China.
Qifan ZhangDepartment of Neurology, People's Hospital of Ningxia Hui Autonomous Region, Yinchuang, Ningxia Hui Autonomous Region 750002, China.ORCID 0000-0003-4840-6141
The Fourth People's Hospital of Ningxia Hui Autonomous Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to systematically evaluate the efficacy and prognosis of acyclovir combined with naloxone in the treatment of patients with viral encephalitis (VE). Methods: PubMed, Web of Science, Embase, CNKI, and WanFang Data were searched for relevant literature published between 2000 and 2021. Meta-analysis was performed using Stata16.0 software. The treatment group was treated with acyclovir combined with naloxone, and the control group was treated with acyclovir alone. Results: A total of 12 studies with 986 participants were included. Compared with the control group, the treatment group could not only significantly improve the treatment response rate (OR = 5.53, 95% CI: 3.50, 8.74; Conclusion: A combination of acyclovir and naloxone can reduce the inflammatory response and shorter the time to symptom relief and disappearance, which is worthy of clinical promotion.

Indexed as

Drugs, Chinese HerbalEncephalitis, ViralAcyclovirHumansNaloxonePrognosisAcyclovirDrugs, Chinese HerbalNaloxone

Identifiers

PMID35399846
PMCPMC8993546
OpenAlexW4226061099

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.