Evidence map›Paper›PMID 35399843›Full record

ArticleJournal of healthcare engineering2022

Treatment Effect of Mometasone Furoate Cream on Lichen Sclerosus et Atrophicus of External Genitalia in Boys and Its Correlation with Toll-Like Receptor 4 and Myeloid Differentiation Factor 88.

Hong Sun, Wei Zhang, Guibo Wang, Chuanwei Sun, Yan Liang, Aijun Li, Qingfeng Li, Jie Lei

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hong SunDepartment of Ediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou City 075000, Hebei Province, China.
Wei ZhangDepartment of Ediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou City 075000, Hebei Province, China.
Guibo WangDepartment of Ediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou City 075000, Hebei Province, China.
Chuanwei SunDepartment of Ediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou City 075000, Hebei Province, China.
Yan LiangDepartment of Ediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou City 075000, Hebei Province, China.
Aijun LiDepartment of Ediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou City 075000, Hebei Province, China.
Qingfeng LiDepartment of Ediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou City 075000, Hebei Province, China.
Jie LeiDepartment of Ediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou City 075000, Hebei Province, China.ORCID 0000-0002-4719-3634
Hebei North University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective is to explore the treatment effect of mometasone furoate cream on lichen sclerosus et atrophicus (LSeA) of external genitalia in boys and its correlation with Toll-like receptor 4 (TLR4) and myeloid differentiation factor 88 (MyD88). Methods: A total of 100 boys treated in our hospital from January 2021 to January 2023 due to clinical manifestations in the external genitalia were selected as the study objects. All boys received redundant circumcision treatment, their protein expression of TLR4 and MyD88 in foreskin tissues was measured by BCA protein assay and western blot, and mometasone furoate cream was applied to those who were pathologically diagnosed with LSeA, so as to compare the levels of serum inflammatory factors and urodynamic indicators in the child patients before and after treatment. Results: The total clinical efficacy rate of LSeA child patients was up to 90.79%; after treatment, the maximum and mean urinary flow rates of child patients were significantly higher than before treatment ( Conclusion: LSeA will increase the inflammatory reactions in child patients, and its pathogenesis may be related to the upregulation of TLR4, MyD88, NF-

Indexed as

Lichen Sclerosus et AtrophicusMyeloid Differentiation Factor 88Toll-Like Receptor 4ChildGenitaliaHumansInflammationMaleMometasone FuroateNF-kappa BMometasone FuroateMYD88 protein, humanMyeloid Differentiation Factor 88NF-kappa BTLR4 protein, humanToll-Like Receptor 4

Identifiers

PMID35399843
PMCPMC8989574
OpenAlexW4220734376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.