Evidence map›Paper›PMID 35399770›Full record

ArticleJournal of conservative dentistry : JCD

Evaluation of

Sarita Bhandari, Rony T Kondody, Arathi S Nair, Rhea Mathew, K P Divakar, Manjusha Nambiar

Open access · hybridAbstract read
In one paragraph

Article in Journal of conservative dentistry : JCD. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sarita BhandariDepartment of Conservative Dentistry and Endodontics, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Rony T KondodyDepartment of Orthodontics and Dentofacial Orthopedics, Sri Rajiv Gandhi College of Dental Sciences, Bengaluru, Karnataka, India.
Arathi S NairDepartment of Conservative Dentistry and Endodontics, Sri Rajiv Gandhi College of Dental Sciences, Bengaluru, Karnataka, India.
Rhea MathewDepartment of Conservative Dentistry and Endodontics, Sri Rajiv Gandhi College of Dental Sciences, Bengaluru, Karnataka, India.
K P DivakarDepartment of Conservative Dentistry and Endodontics, ESIC Dental College and Hospital, Gulbarga, Karnataka, India.
Manjusha NambiarDepartments of periodontics, Sri Rajiv Gandhi College of Dental Sciences, Bengaluru, Karnataka, India.
Sri Rajiv Gandhi College of Dental Sciences and Hospital · INESIC Hospital · INSharda University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Proper hybrid layer formation lays the foundation of resin-dentin bonding. The resin infiltration in demineralized dentin collagen couples with the adhesive/resin composites in the mineralized dentin surface. However, the activation of enzymatic activity in the collagen matrix can degrade the hybrid layer. Over the time, it leads to reduced bond strength. Mainly, the enzymes involved are matrix metalloproteinases (MMPs) which are involved in degrading most of the extracellular matrix components. Aims: The purpose of the study was designed for evaluating the inhibitory action of Materials and Methods: A total of 15 freshly extracted healthy human teeth were collected and stored at 4°C until use. The roots were separated. The enamel and remnant pulp tissue were removed, and collected teeth were pulverized with liquid nitrogen in the minimum volume of 50-mM phosphate buffer to obtain dentin powder extract. The dentin powder extract is the source of MMPs, and therefore, the extract was treated with Results: Conclusions:

Indexed as

Aloe vera extractmatrix metalloproteinasesplate assay methodzymogram activity

Identifiers

PMID35399770
PMCPMC8989161
OpenAlexW4214808107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.