Evidence map›Paper›PMID 35399584›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2022

Continuous Positive Airway Pressure Adherence and Treatment Cost in Patients With Obstructive Sleep Apnea and Cardiovascular Disease.

Joshua M Bock, Keith A Needham, David A Gregory, Mercedes M Ekono, Emerson M Wickwire, Virend K Somers, Amir Lerman

Abstract read
In one paragraph

Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Breathe Better and Preserve Heart.Journal of the American Heart Association · 2023
    Article
  11. Article
  12. Article
  13. Personalized Medicine and Obstructive Sleep Apnea.Journal of personalized medicine · 2022
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joshua M BockDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Keith A NeedhamBaker Tilly US LLP, New York, NY.
David A GregoryBaker Tilly US LLP, New York, NY.
Mercedes M EkonoBaker Tilly US LLP, New York, NY.
Emerson M WickwireSleep Disorders Center, Division of Pulmonary and Critical Care, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
Virend K SomersDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Amir LermanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.

Funding

CARDIOVASOLOGYT32HL007111 · NHLBI · MAYO CLINIC ROCHESTER · PI Barry A. Borlaug · 1985 to 2026
$8.7M
NHLBI NIH HHS T32 HL007111
6 · The paper itself

Abstract

Objective: To determine whether continuous positive airway pressure (CPAP) adherence reduces health care-related costs or use in patients with obstructive sleep apnea (OSA) and comorbid cardiovascular disease (CVD). Patients: A total of 23 million patients with CVD were identified in the Medicare fee-for-service database. Of the 65,198 who completed a sleep study between January 2016 and September 2018, 55,125 were diagnosed as having OSA and 1758 were identified in the 5% Medicare durable medical equipment (DME) database. Methods: Patients with DME claims were categorized as adherent (AD, treatment evidenced ≥91 days after CPAP initiation; n=614) or nonadherent (nAD, n=242) to CPAP therapy. In addition, 9881 individuals with CVD who were not diagnosed as having OSA after sleep testing and without CPAP initiation were included as control patients. Propensity score matching balanced the groups for age, sex, and comorbidities (eg, diabetes mellitus), resulting in 241 participants per cohort. Dependent variables included total episode-of-care, inpatient, outpatient, skilled nursing, home health, and DME costs across 12 months. Results: Total episode-of-care costs of AD participants ($6825) were lower than those of nAD ($11,312; Conclusion: Adherence to CPAP treatment reduces annual health care-related expenses by 40% in Medicare patients with CVD and OSA.

Indexed as

AD, patients adherent to continuous positive airway pressure treatmentCAD, coronary artery diseaseCPAP, continuous positive airway pressureCVD, cardiovascular diseaseDME, durable medical equipmentEOC, episode of careFFS, fee-for-serviceHSAT, in-home sleep apnea testICD-10, International Statistical Classification of Diseases, Tenth RevisionLOS, length of stayMA, Medicare AdvantagenAD, patients nonadherent to continuous positive airway pressure treatmentOSA, obstructive sleep apneaPSG, polysomnographyPSM, propensity score matching

Identifiers

PMID35399584
PMCPMC8987617

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.