ArticleTranslational lung cancer research2022
The clinical characteristics, treatments and prognosis of post-esophagectomy airway fistula: a multicenter cohort study.
Article in Translational lung cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Recurrent Cervical Esophageal Fistula and Retroesophageal Abscess Following Surgical Management of Zenker's Diverticulum.Journal of clinical medicine · 2026Article
- A review of management of benign post-esophagectomy respiratory-digestive fistula in esophageal cancer in China.Esophagus : official journal of the Japan Esophageal Society · 2026Review
- Effective management of cervical anastomotic leakage post-esophageal cancer surgery using negative pressure wound therapy with saline instillation: A case report.Asia-Pacific journal of oncology nursing · 2025Article
- Single staged repair of an anastomotic tracheal fistula following Mckeown esophagectomy via cervical incision: a case report.Journal of cardiothoracic surgery · 2025Article
- Endoluminal Wound Vacuum Therapy: A Paradigm Shift in Managing Esophageal Bronchial Fistula.Annals of thoracic surgery short reports · 2024Article
- Efficiency and Complications of Esophageal Stenting in the Management of Postoperative Fistulas.Journal of clinical medicine · 2024Article
- A approach of gastric conduit via the anterior of pulmonary hilum route during minimally invasive McKeown esophagectomy.Journal of cardiothoracic surgery · 2024Article
- Management and outcomes in a consecutive series of patients with aero-digestive fistula at a tertiary gastro-esophageal surgery center.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Article
- Surgical treatment of esophago-tracheobronchial fistulas after esophagectomy.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Article
- Duodenal diversion surgery in management of intractable tracheobroncho-gastric fistula after esophagectomy.General thoracic and cardiovascular surgery cases · 2023Article
- Management of aero-digestive fistulas in adults: the bronchoscopist's perspective.Mediastinum (Hong Kong, China) · 2023Review
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15 authors.
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Abstract
Background: Post-esophagectomy airway fistula (PEAF) is a serious complication after esophageal cancer resection. At present, the clinical characteristics, treatments and prognosis of PEAF patients remain inconclusive. We aimed to investigate these problems of patients with PEAF through a multi-center retrospective cohort study. Methods: We included consecutive patients who underwent esophagectomy for esophageal cancer in seven major Chinese esophageal cancer centers from January 2010 to December 2020. Based on the anatomic characteristics of PEAF patients, PEAFs were divided into Union type I (without digestive fistula) and Union type II [respiratory-digestive fistula (RDF)], and subtypes a and b (tracheal or bronchial fistulas), as well as L1 and L2 (same or different level of fistulas). The clinical characteristics, diagnoses, managements, and effects of the various types were retrospectively analyzed. Results: PEAF occurred in 85 of 26,608 patients (0.32%), including eight females and 77 males. There were 16 patients with type I and 69 with type II. The numbers of healings, non-healings, and deaths at discharge were 45 (52.9%), 20 (23.5%), and 20 (23.5%), respectively. Type Ib was common in type I, and type II L1 was common in type II. The healing rates of surgical, stent, and conservative treatments were 50%, 60%, and 50%, respectively. All type I patients treated with stent implantation were healed at discharge. The healing rates, mortality, and 3-year survival of type II L1 and type II L2 patients were 55.4% and 30.8%, 17.9% and 30.8%, and 34.3% and 15.4%, respectively. The 5-year survival rates of all PEAFs were 21.1%. Conclusions: PEAF is an infrequent and life-threatening complication after esophagectomy. Patients with different types of PEAF often have different inducements. In this study, we found that the healing rates of surgical and conservative treatments were similar, and stent implantation may have the potential to improve efficacy. Type II L2 patients were the most difficult to cure.
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