Evidence map›Paper›PMID 35399566›Full record

ArticleTranslational lung cancer research2022

The downregulation of fibrinogen-like protein 1 inhibits the proliferation of lung adenocarcinoma via regulating

Xi-Yang Tang, Yan-Lu Xiong, An-Ping Shi, Ying Sun, Qing Han, Yao Lv, Xian-Gui Shi, Milo Frattini, Jyoti Malhotra, Kai-Fu Zheng and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Translational lung cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. GATA1 knockdown enhances CD8Journal of molecular histology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Xi-Yang Tang *Department of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yan-Lu Xiong *Department of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
An-Ping Shi *Department of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Fourth Military Medical University (Air Force Medical University), Xi'an, China.
Ying Sun *Department of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Qing HanCollege of Basic Medicine, Air Force Medical University, Xi'an, China.
Yao LvCollege of Basic Medicine, Air Force Medical University, Xi'an, China.
Xian-Gui ShiCollege of Basic Medicine, Air Force Medical University, Xi'an, China.
Milo FrattiniLaboratory of Molecular Pathology, Institute of Pathology (ICP), Cantonal Hospital (EOC), Locarno, Switzerland.
Jyoti MalhotraRutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Kai-Fu ZhengDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yu-Jian LiuDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Tao JiangDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Nan MaDepartment of Ophthalmology, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Jin-Bo ZhaoDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Air Force Medical University · CNIstituto Cantonale di Patologia · CHRutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The mechanisms involved in the malignant progression of lung adenocarcinoma (LUAD) are still inconclusive. Fibrinogen-like protein 1 ( Methods: Differential gene expression of Results: Multiple databases showed that Conclusions:

Indexed as

fibrinogen-like protein 1 (FGL1)Immune checkpointlung adenocarcinoma (LUAD)proliferation

Identifiers

PMID35399566
PMCPMC8988074
OpenAlexW4223447573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.