Evidence map›Paper›PMID 35399550›Full record

ReviewCardiac failure review2022

The Impact of Frailty and Comorbidities on Heart Failure Outcomes.

Thomas Salmon, Hani Essa, Behnam Tajik, Masoud Isanejad, Asangaedem Akpan, Rajiv Sankaranarayanan

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cardiac failure review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05888688 (The Imaging Assessment of Sarcopenia Across the Heart Failure Spectrum), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05888688 recruitingnot on this mapstarted 2023, after this paper: background citation

The Imaging Assessment of Sarcopenia Across the Heart Failure Spectrum

Typeobservational_patient_registrySponsorUniversity of LeicesterRan2023 to 2026Enrolled80ConditionsHeart Failure, Sarcopenia, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  10. Observational
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Thomas SalmonDepartment of Cardiology, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust Liverpool, UK.
Hani EssaDepartment of Cardiology, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust Liverpool, UK.
Behnam TajikInstitute of Public Health and Clinical Nutrition, University of Eastern Finland Kuopio, Finland.
Masoud IsanejadLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool Heart & Chest Hospital Liverpool, UK.
Asangaedem AkpanDepartment of Cardiology, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust Liverpool, UK.
Rajiv SankaranarayananDepartment of Cardiology, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust Liverpool, UK.
University of Liverpool · GBUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frailty is a multisystemic process leading to reduction of physiological reserve and a reduction in physical activity. Heart failure (HF) is recognised as a global cause of morbidity and mortality, increasing in prevalence over recent decades. Because of shared phenotypes and comorbidities, there is significant overlap and a bidirectional relationship, with frail patients being at increased risk of developing HF and vice versa. Despite this, frailty is not routinely assessed in patients with HF. Identification of these patients to direct multidisciplinary care is key, and the development of a frailty assessment tool validated in a large HF population is also an unmet need that would be of considerable benefit in directing multidisciplinary-team management. Non-pharmacological treatment should be included, as exercise and physical rehabilitation programmes offer dual benefit in frail HF patients, by treating both conditions simultaneously. The evidence for nutritional supplementation is mixed, but there is evidence that a personalised approach to nutritional support in frail HF patients can improve outcomes.

Indexed as

comorbidityFrailtyheart failure

Identifiers

PMID35399550
PMCPMC8977991
OpenAlexW4221058851

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.