Evidence map›Paper›PMID 35399507›Full record

ReviewFrontiers in cell and developmental biology2022

The Impact of Metabolic Syndrome and Type 2 Diabetes

André P Sousa, Raquel Costa, Marco G Alves, Raquel Soares, Pilar Baylina, Rúben Fernandes

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Metabolic convergence of diabetes and prostate cancer: from dysglycemia to tumor microenvironment reprogramming.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

André P SousaLaBMI-Laboratório de Biotecnologia Médica e Industrial, Porto, Portugal.
Raquel CostaLaBMI-Laboratório de Biotecnologia Médica e Industrial, Porto, Portugal.
Marco G AlvesICBAS-Instituto de Ciências Biomédicas Abel Salazar, Porto, Portugal.
Raquel SoaresDepartment of Biomedicine, Unit of Biochemistry, Faculty of Medicine of Porto University, Porto, Portugal.
Pilar BaylinaLaBMI-Laboratório de Biotecnologia Médica e Industrial, Porto, Portugal.
Rúben FernandesLaBMI-Laboratório de Biotecnologia Médica e Industrial, Porto, Portugal.
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTUniversidade do Porto · PTPolytechnic Institute of Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) remains the second most common type of cancer in men worldwide in 2020. Despite its low death rate, the need for new therapies or prevention strategies is critical. The prostate carcinogenesis process is complex and multifactorial. PCa is caused by a variety of mutations and carcinogenic events that constitutes the disease's multifactorial focus, capable of not only remodeling cellular activity, but also modeling metabolic pathways to allow adaptation to the nutritional requirements of the tumor, creating a propitious microenvironment. Some risk factors have been linked to the development of PCa, including Metabolic Syndrome (MetS) and Type 2 Diabetes

Indexed as

cancer biologydiabetesmetabolic syndromemetabolismprostate cancersignaling/signaling pathways

Identifiers

PMID35399507
PMCPMC8992047
OpenAlexW4220777552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.